NCT02961348Completed
TIMING of Oral Anticoagulant Therapy in Acute Ischemic Stroke With Atrial Fibrillation
Timing of Oral Anticoagulant Therapy in Acute Ischemic Stroke With Atrial Fibrillation: a Prospective Multicenter Registry-based Non-inferiority Randomized Controlled Clinical Trial
Source: ClinicalTrials.gov · Last updated 16 May 2024
Brief summary (registry, in English)
This study will compare early with late start of treatment with Non-vitamin K oral anticoagulation (NOAC) in adult patients with acute ischemic stroke and atrial fibrillation; it is a registry-based randomized clinical trial (R-RCT) using The Swedish Stroke Register (Riksstroke). Half of the patients will start NOAC early (within 4 days after stroke onset) while the other half will start late (5-10 days after stroke onset).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 888 (actual)
- First submitted
- 8 Nov 2016
- Start date
- 15 Feb 2017
- Primary completion date
- 10 Jun 2021
- Lead sponsor
- Uppsala University
- Diseases
- Stroke, Atrial fibrillation
- NCT number
- NCT02961348
What you commit to
- Study type: Interventional
- Participants enrolled: 888
- From 15 Feb 2017 to the primary completion date, 10 Jun 2021
- 36 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous randomization in the TIMING study
Other illness
- Contraindication to NOAC (e.g. ongoing bleeding, mechanical heart valve prosthesis)
- Ongoing therapy with NOAC (without ≥2 days interruption at index stroke)
Lab values
- International normalized ratio (INR)\>1.7
Other
- No second brain imaging (CT/MRI) after thrombolysis/thrombectomy
Who the study is looking for
- Adult patients (≥ 18 years) with acute ischemic stroke and atrial fibrillation
- Eligible and willing to start (or re-start) NOAC
- Registered in The Swedish Stroke Register
- Signed informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (36)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Alingås Hospital Coordinator of this site? Confirm its status | Alingsås | Sweden | Unknown status |
| Enköping Hospital Coordinator of this site? Confirm its status | Enköping | Sweden | Unknown status |
| Mälarsjukhuset Hospital Coordinator of this site? Confirm its status | Eskilstuna | Sweden | Unknown status |
| Falu Hospital Coordinator of this site? Confirm its status | Falun | Sweden | Unknown status |
| Gävle Hospital Coordinator of this site? Confirm its status | Gävle | Sweden | Unknown status |
| Sahlgrenska University Hospital Coordinator of this site? Confirm its status | Gothenburg | Sweden | Unknown status |
| Sahlgrenska University Hospital/Östra Coordinator of this site? Confirm its status | Gothenburg | Sweden | Unknown status |
| Hallands Hospital Coordinator of this site? Confirm its status | Halmstad | Sweden | Unknown status |
| Hässleholm Hospital Coordinator of this site? Confirm its status | Hässleholm | Sweden | Unknown status |
| Helsingborg hospital Coordinator of this site? Confirm its status | Helsingborg | Sweden | Unknown status |
| Karolinska University Hospital, Huddinge Coordinator of this site? Confirm its status | Huddinge | Sweden | Unknown status |
| Hudiksvalls sjukhus Coordinator of this site? Confirm its status | Hudiksvall | Sweden | Unknown status |
| Ryhov Coordinator of this site? Confirm its status | Jönköping | Sweden | Unknown status |
| Kalmar Hopsital Coordinator of this site? Confirm its status | Kalmar | Sweden | Unknown status |
| Länssjukhuset Kalmar Coordinator of this site? Confirm its status | Kalmar | Sweden | Unknown status |
| Kiruna Hospital Coordinator of this site? Confirm its status | Kiruna | Sweden | Unknown status |
| Köping Hospital Coordinator of this site? Confirm its status | Köping | Sweden | Unknown status |
| Kungälv Hospital Coordinator of this site? Confirm its status | Kungälv | Sweden | Unknown status |
| Lindesberg Hospital Coordinator of this site? Confirm its status | Lindesberg | Sweden | Unknown status |
| Lund Coordinator of this site? Confirm its status | Lund | Sweden | Unknown status |
| Malmö University Hospital Coordinator of this site? Confirm its status | Malmö | Sweden | Unknown status |
| Sahlgrenska Universitetssjukhuset Mölndal Coordinator of this site? Confirm its status | Mölndal | Sweden | Unknown status |
| Motala Hospital Coordinator of this site? Confirm its status | Motala | Sweden | Unknown status |
| Nyköping Hospital Coordinator of this site? Confirm its status | Nyköping | Sweden | Unknown status |
| Örebro University Hospital Coordinator of this site? Confirm its status | Örebro | Sweden | Unknown status |
| Oskarshamn Hospital Coordinator of this site? Confirm its status | Oskarshamn | Sweden | Unknown status |
| Skaraborg Hospital Coordinator of this site? Confirm its status | Skövde | Sweden | Unknown status |
| Karolinska University Hospital Coordinator of this site? Confirm its status | Solna | Sweden | Unknown status |
| Södersjukhuset Coordinator of this site? Confirm its status | Stockholm | Sweden | Unknown status |
| Capio S:t Görans hospital Coordinator of this site? Confirm its status | Stockholm | Sweden | Unknown status |
| Danderyd University Hospital Coordinator of this site? Confirm its status | Stockholm | Sweden | Unknown status |
| Sundsvall County Hospital Coordinator of this site? Confirm its status | Sundsvall | Sweden | Unknown status |
| University Hospital of Umeå Coordinator of this site? Confirm its status | Umeå | Sweden | Unknown status |
| Uppsala University Hospital Coordinator of this site? Confirm its status | Uppsala | Sweden | Unknown status |
| Hallands Hospital Coordinator of this site? Confirm its status | Varberg | Sweden | Unknown status |
| Västerås Hospital Coordinator of this site? Confirm its status | Västerås | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.