NCT02972580Active, not recruiting
Characterization of Clinical Skeletal and Cardiac Impairment in Carriers of DMD and BMD
Characterization of Clinical Skeletal and Cardiac Impairment in Carriers of Duchenne Muscular Dystrophy (DMD) and Becker Muscular Dystrophy (BMD)
Source: ClinicalTrials.gov · Last updated 27 Aug 2024
Brief summary (registry, in English)
Longitudinal prospective observational study. This is a 24-month study with the possibility of extending the data time points. Initially baseline, then 12 and 24 months follow up studies will be completed.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 250 (estimated)
- First submitted
- 25 Jul 2016
- Start date
- Jun 2016
- Primary completion date
- Dec 2030
- Lead sponsor
- Nationwide Children's Hospital
- Diseases
- Duchenne muscular dystrophy
- NCT number
- NCT02972580
What you commit to
- Study type: Observational
- Planned participants: 250
- From Jun 2016 to the primary completion date, Dec 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Subjects on steroid treatment
Other illness
- Subjects with a contraindication to cardiac or skeletal muscle MRI
- Subjects on heart failure medication at time of enrollment
- Presence of an inherited neurologic disease or comorbidity that may affect their ability to complete this study
- Has a medical condition or extenuating circumstance that, in the opinion of the investigator, might compromise the subject's ability to comply with the protocol required testing or procedures or compromise the subject's wellbeing, safety, or clinical interpretability
Who the study is looking for
- Age \>18 years
- Cohort A requires a genetically confirmed mutation in the DMD gene with an affected child
- Cohort B includes DMD/BMD mothers with NO somatic mutation in the DMD gene
- Cohort C age-matched healthy controls with a normal CK level
- Cohort D requires a genetically confirmed mutation in the DMD gene without an affected child
- Able to complete testing in English
- Able to consent
Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nationwide Children's Hosptial Coordinator of this site? Confirm its status | Columbus | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.