NCT02994121Recruiting
Prospective Investigation of Multiple Sclerosis in the Three Rivers Region
Source: ClinicalTrials.gov · Last updated 29 Dec 2025
Brief summary (registry, in English)
In this longitudinal prospective natural history study of multiple sclerosis (MS), the overarching goal is to understand the factors that influence individual variation in disease trajectory and treatment response and pave the way for realizing precision medicine in MS. Because MS is a chronic neurological disorder, this observational cohort study will span a 30-year time frame.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 7500 (estimated)
- First submitted
- 12 Dec 2016
- Start date
- Dec 2016
- Primary completion date
- Jan 2047
- Lead sponsor
- University of Pittsburgh
- Diseases
- Multiple sclerosis
- NCT number
- NCT02994121
What you commit to
- Study type: Observational
- Planned participants: 7500
- From Dec 2016 to the primary completion date, Jan 2047
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Inclusion criteria for MS patients include:
- Age 7 years or older
- Willing and able to provide consent (for \>=18 years) or assent with permission from at least one of the child's parents (for \<18 years)
- Diagnosis of multiple sclerosis or related disorders, including a first central nervous system demyelinating episode with a positive MRI scan or abnormal MRI scans characteristic of MS but no clinical symptoms of the disease
- For healthy controls:
- Age 7 years or older
- Willing and able to provide consent (for \>=18 years) or assent with permission from at least one of the child's parents (for \<18 years)
- No known personal history of multiple sclerosis or related disorders
- No other chronic diseases
- Family members, unrelated household controls, or controls from the general population could be eligible
- There is no exclusion criteria.
Age in the registry: 7 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Pittsburgh Coordinator of this site? Confirm its status | Pittsburgh | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.