NCT03048370Completed
Reactivity of the Vestibular System to Caloric Vestibular Stimulation in Schizophrenia
Source: ClinicalTrials.gov · Last updated 8 Feb 2024
Brief summary (registry, in English)
This study aims to determine if individuals with schizophrenia have greater reactivity to vestibular stimulation than healthy controls. The physiological response of vestibular stimulation will be assessed with electronystagmography, which provides a measure of the intensity of the nystagmus via PSPV. Positive results would suggest greater vestibular system reactivity to vestibular stimulation may be a biomarker of schizophrenia. Pathophysiologically, increased vestibular reactivity to vestibular stimulation may reflect abnormal vestibular function or impaired central suppression of the vestibular ocular reflex.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 14 Dec 2016
- Start date
- 1 Jan 2019
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Centre for Addiction and Mental Health
- Diseases
- Schizophrenia
- NCT number
- NCT03048370
What you commit to
- Study type: Interventional
- Participants enrolled: 40
- From 1 Jan 2019 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Serious unstable medical illness or any concomitant major medical or neurological illness
- DSM-IV substance dependence (except caffeine and nicotine) within one month prior to entering the study
- Positive urine drug screen
- History or signs of middle ear surgery (e.g. Tympanoplasty, mastoidectomy)
Other illness
- Formal thought disorder rating of over 2 on the Scale for Assessment of Positive Symptoms (SAPS) \[patients only\]
- History of external or middle ear pathology
- Signs of active ear disease
Other
- Acute suicidal and/or homicidal ideation
- Pregnant women
Who the study is looking for
- Male or female inpatients or outpatients age ≥18
- Having a DSM-5 diagnosis of schizophrenia or schizoaffective disorder
- Voluntary and capable of consenting to participation in the research study
- Fluent in English
- Male or female and age ≥18
- Voluntary and capable of consenting to participation in the research study
- Fluent in English
- Absence of history of psychiatric illness using the Mini-International Neuropsychiatric Interview (MINI)
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre for Addiction and Mental Health Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.