NCT03068663Active, not recruiting
Microbiota and the Lung Cancer
Characterization of Microbiota (Intestinal, From Lungs, and Upper Airways) in Patients With Non-small Cell Lung Carcinoma: Exploratory Study
Source: ClinicalTrials.gov · Last updated 20 Mar 2026
Brief summary (registry, in English)
The subject is to study the lung microbiota and the one of upper airways (UAs) (much less studied than the intestinal microbiota) in 40 patients having lung cancer. 20 patients undergo only surgical treatment, while other half receives also chemotherapy. The idea is to explore changes in microbiota of the lung, upper UAs and intestine, and potentially find associations between them. These results will serve us as a base for the future study, focused on manipulation of the microbiota by prebiotics, probiotics or symbiotics and its effect on anti-cancer treatment tolerance and effectiveness.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 27 Feb 2017
- Start date
- 23 May 2017
- Primary completion date
- 30 Oct 2029
- Lead sponsor
- Centre Jean Perrin
- Diseases
- Lung cancer
- NCT number
- NCT03068663
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 23 May 2017 to the primary completion date, 30 Oct 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- concurrent treatment with experimental medication, participation in another clinical therapeutic study within 30 days
- previous esophageal surgery
- previous ORL (otho-rhino-laryngo) cancer treated by radiotherapy or surgery
Other illness
- digestive or pulmonary infection of a long duration during the two months preceding the study (with antibiotic treatment)
Other
- cognitive difficulties
- refusal of participation or inability to give a clear consent
- inflammatory digestive pathology
- presence of colostomy, total or partial gastrectomy
- patient enable to follow the requirements of the study
- patient deprived of his rights by administrative or judicial decision
Who the study is looking for
- non small cell lung carcinoma patient suitable for surgery, or chemotherapy followed by surgery
- BMI \<29.9 kg/m²
- not taking antibiotics, corticosteroids and/or immunosuppressants at least during two months before inclusion
- not taking prebiotics, probiotics or symbiotics at least during two months before inclusion
- signing the written consent before enrollment in the study
- affiliation to the national health insurance (or system alike) according to the law from 9th August 2004
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Jean Perrin Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.