NCT03073278Recruiting
Focal Radiotherapy for Previously Treated Prostate Cancer Patients
Phase I Feasibility Trial of Stereotactic Re-irradiation of Prostate Cancer Recurrence Within the Definitively Irradiated Prostate
Source: ClinicalTrials.gov · Last updated 6 Feb 2026
Brief summary (registry, in English)
To examine the feasibility, safety and toxicity of focal stereotactic radiation treatment (SBRT) for locally recurrent prostate cancer.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 36 (estimated)
- First submitted
- 27 Feb 2017
- Start date
- 24 Apr 2017
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- Royal North Shore Hospital
- Diseases
- Prostate cancer
- NCT number
- NCT03073278
What you commit to
- Study type: Interventional
- Planned participants: 36
- From 24 Apr 2017 to the primary completion date, 31 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Grade 3 or more toxicity from previous EBRT
- GS 8,9 or 10 disease previously (relative - consider if decent disease free interval)
Other
- Recurrence in immediate proximity to rectum (unless able to have hydrogel)
- Contra-indicated for fiducial insertion
Who the study is looking for
- Men \> 4yrs from external beam radiotherapy (EBRT) meeting the Phoenix definition of biochemical failure or men \> 5yrs from EBRT if neo-adjuvant and/or adjuvant androgen deprivation therapy (ADT) also used
- Recurrence localised to less than 1 lobe of prostate on both PMSA and multi-parametric MRI (less than equal to cT2a)
- Recurrence must be biopsy proven, with positive biopsies limited to the PET and MRI suspicious region.
- Life expectancy at least 10yrs from time of SBRT
- PSA \< 10
Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Royal North Shore Hospital Coordinator of this site? Confirm its status | St Leonards | Australia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.