NCT03076034Active, not recruiting
Utility of Cortical Bone Tissue Properties in the Assessment of Fracture Risk
Source: ClinicalTrials.gov · Last updated 28 Oct 2025
Brief summary (registry, in English)
The objective of this study is to determine whether a new minimally invasive method for in vivo measurement of cortical bone tissue properties can identify those who are at risk for fragility fractures of the hip and radius. The investigators hypothesis is that women with fragility fractures of the hip and radius have altered cortical bone tissue properties compared to non-fracture controls independent of standard clinical tests, such as bone mineral density (BMD) by dual-energy x-ray absorptiometry (DXA).
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 190 (estimated)
- First submitted
- 6 Mar 2017
- Start date
- 26 Jan 2015
- Primary completion date
- 8 Aug 2026
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Diseases
- Osteoporosis
- NCT number
- NCT03076034
What you commit to
- Study type: Interventional
- Planned participants: 190
- From 26 Jan 2015 to the primary completion date, 8 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Treatment with bisphosphonate, estrogen (within previous 3 years), teriparatide therapy, calcitonin, selective estrogen receptor modulator (SERMs,within previous 3 years)
- Prior fracture in adulthood (\>age 18) for healthy controls
- Amendment to protocol added Arm 2, to include males \>50 years with otherwise similar eligibility criteria.
Other illness
- History of skeletal metastasis, primary hyperparathyroidism, Paget's disease, multiple myeloma
Other
- Unable to undergo BMD by DXA or high-resolution peripheral quantitative computed tomography (HR-pQCT)
- Use of glucocorticoids continuously for more than 3 months, use of anticonvulsants
Who the study is looking for
- Women with hip and wrist fractures within 2 weeks of presentation
- Non-fracture controls
Age in the registry: 50 years to 100 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Beth Israel Deaconess Medical Center Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.