NCT03104569Not yet recruiting
Effect of 37℃ Non-ionic Contrast Agent During ERCP Procedure in Hilar Cholangiocarcinoma
Effect of 37℃ Non-ionic Contrast Agent During ERCP Procedure in Hilar Cholangiocarcinoma: A Prospective Double-blind Multicenter Randomized Controlled Study
Source: ClinicalTrials.gov · Last updated 26 Dec 2025
Brief summary (registry, in English)
The purpose of this study is to determine the effect of normal temperature and 37℃ non-ionic contrast agent acting on ERCP-related cholangeitis after endoscopic retrograde cholangiopancreatography (ERCP) in the treatment of hilar cholangiocarcinoma.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 26 Mar 2017
- Start date
- 1 Apr 2026
- Primary completion date
- 1 Dec 2028
- Lead sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT03104569
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 1 Apr 2026 to the primary completion date, 1 Dec 2028
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous ERCP;
Other illness
- Preoperative hemobilia or hemorrhage of digestive tract;
- Preoperative liver failure;
- Combined with Mirizzi syndrome and intrahepatic bile duct stones;
- Preoperative malignant tumor of biliary system such as carcinoma of head of pancreas, gallbladder carcinoma;
- Biliary-duodenal fistula confirmed during ERCP;
- A history of reconstructive surgery for upper digestive tract except Billroth Ⅰand a history of cholangioenterostomy including cholangio-jejunostomy and side to side anastomosis of the bile duct and duodenum;
Lab values
- Coagulation dysfunction(INR\>1.3) or/and low peripheral blood platelet count （PLT \<50x10\^9/L）;
Other
- Preoperative acute cholangitis;
- Preoperative acute pancreatitis;
- Pregnant women
Who the study is looking for
- Type Ⅰ、Ⅱ、Ⅲ、Ⅳ of Hilar Cholangiocarcinoma;
- Age: 18\~90 years old;
- Underwent diagnostic and therapeutic ERCP;
Age in the registry: 18 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Hospital of Lanzhou University Coordinator of this site? Confirm its status | Lanzhou | China | Unknown status |
| Tianjin Nankai Hospital Coordinator of this site? Confirm its status | Tianjin | China | Unknown status |
| The First Affiliated Hospital of Xi'an Jiaotong University Coordinator of this site? Confirm its status | Xi’an | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.