NCT03119883Completed
Dysregulation of Glutamine Activity in the Pathogenesis of Multiple Myeloma
Dysregulation of Glutamine Utilization in the Pathogenesis of Multiple Myeloma
Source: ClinicalTrials.gov · Last updated 9 Aug 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This clinical trial studies the utilization of glutamine by the bone marrow plasma cells from patients with monoclonal gammopathy of undetermined significance (MGUS) compared to multiple myeloma (MM). Results from this study may identify metabolic differences between pre-malignant and malignant clonal plasma cells in MGUS and MM, respectively. It may also allow researchers better determine the transition from MGUS to MM for the development of potential early diagnostic purposes of preventative strategies.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 35 (actual)
- First submitted
- 12 Apr 2017
- Start date
- 2 Jun 2017
- Primary completion date
- 30 Jun 2024
- Lead sponsor
- Mayo Clinic
- Diseases
- Multiple myeloma
- NCT number
- NCT03119883
What you commit to
- Study type: Interventional
- Participants enrolled: 35
- From 2 Jun 2017 to the primary completion date, 30 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior history of adverse events with conscious sedation
Lab values
- Hemoglobin \< 8 g/dL
Other
- Unable to provide consent
- Eastern Cooperative Oncology Group (ECOG) performance status (PS) \> 3
- Women who are pregnant
Who the study is looking for
- At least 18 years of age
- International Myeloma Working Group (IMWG) criteria for the diagnosis of either MGUS or MM
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic in Rochester Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.