NCT03127059Completed
Breathing Exercises in Asthma Targeting Dysfunctional Breathing
BEAT DB-study; Breathing Exercises in Asthma Targeting Dysfunctional Breathing-a Randomised Controlled Trial
Source: ClinicalTrials.gov · Last updated 9 Jun 2026
Brief summary (registry, in English)
Dyspnoe can disable patients with asthma. Dysfunctional breathing (DB), resulting in dyspnoe, can mimic or exaggerate asthma. Around every forth patient with asthma have DB. Breathing exercises (BrEX) can improve asthma-related quality of live (QOL) in less severe asthma. No study has investigated the effect of BrEX on QOL neither on level of physical activity in severe asthma. A randomised controlled multicentre trial will include 190 adults with poor asthma control (Asthma Control Questionnaire (ACQ6)-score≥0.8) from seven outpatient departments and one specialized private clinic. Patients will be allocated to either usual care (no intervention) or breathing exercises (BrEX)-treatment consisting of 12-week intervention including three physiotherapist-sessions focusing on breathing pattern modification (Papworth Method; Buteyko technique) in rest and activity and 10 minutes home-exercise twice daily. Primary outcome is change in Mini Asthma Quality of Life Questionnaire (MiniAQLQ) at six-months follow-up.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 193 (actual)
- First submitted
- 20 Apr 2017
- Start date
- 27 Apr 2017
- Primary completion date
- 14 Apr 2020
- Lead sponsor
- Naestved Hospital
- Diseases
- Asthma
- NCT number
- NCT03127059
What you commit to
- Study type: Interventional
- Participants enrolled: 193
- From 27 Apr 2017 to the primary completion date, 14 Apr 2020
- 8 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any severe disease as judged by the responsible physician
Age
- Aged \<18
Other
- Trained in breathing exercises by physiotherapist last 6 months
- Pregnancy
- Not able to speak, read or understand Danish
- Participating in another pulmonary interventional research-project.
Who the study is looking for
- Referred from GP to a secondary, out-patient respiratory clinic for lack of asthma control
- Pulmonologist-diagnosed asthma
- ≥ 2 consultations at a pulmonologist-lead asthma clinic
- ACQ6 ≥0.8
- Able to provide written informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dep. of Physiotherapy and Dep. of Pulmonology Coordinator of this site? Confirm its status | Aalborg | Denmark | Unknown status |
| Dep. of Physiotherapy and Dep. of Pulmonology Coordinator of this site? Confirm its status | Bispebjerg | Denmark | Unknown status |
| Allergi og Lungeklinikken Helsingør Coordinator of this site? Confirm its status | Elsinore | Denmark | Unknown status |
| Dep. of Physiotherapy and Dep. of Pulmonology Coordinator of this site? Confirm its status | Hvidovre | Denmark | Unknown status |
| Dep. of Physiotherapy and Dep. of Pulmonology Coordinator of this site? Confirm its status | Næstved | Denmark | Unknown status |
| Dep. of Physiotherapy and Dep. of Pulmonology Coordinator of this site? Confirm its status | Odense | Denmark | Unknown status |
| Dep. of Physiotherapy and Dep. of Pulmonology Coordinator of this site? Confirm its status | Roskilde | Denmark | Unknown status |
| Dep. of Physiotherapy and Dep. of Pulmonology Coordinator of this site? Confirm its status | Silkeborg | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.