NCT03127631Active, not recruiting
A Study for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients
The Role of Androgen Deprivation Therapy In Cardiovascular Disease - A Longitudinal Prostate Cancer Study (RADICAL PC1) & A Randomized Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients (RADICAL PC2)
Source: ClinicalTrials.gov · Last updated 2 Jul 2026
Brief summary (registry, in English)
RADICAL PC1 is a prospective cohort study of men with a new diagnosis of prostate cancer. RADICAL PC2 is a randomized, controlled trial of a systematic approach to modifying cardiovascular and lifestyle risk factors in men with a new diagnosis of prostate cancer.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 5000 (estimated)
- First submitted
- 7 Sept 2016
- Start date
- 21 Oct 2015
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- McMaster University
- Diseases
- Prostate cancer
- NCT number
- NCT03127631
What you commit to
- Study type: Interventional
- Planned participants: 5000
- From 21 Oct 2015 to the primary completion date, 31 Dec 2026
- 61 sites in 9 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Patients will be excluded if they fulfill any of the following:
- are unwilling to provide consent or
- are \<45 years of age, or
- prostate cancer was found incidentally following cystectomy for bladder cancer
Other
- Patients will be eligible for RADICAL PC1, but will not be eligible for RADICAL PC2 if they:
- see a cardiologist every year, or
- both take a statin and have systolic blood pressure ≤130mmHg
Who the study is looking for
- 1\. A man with a diagnosis of prostate cancer that is either:
- new (i.e. the diagnosis was made within 1 year of the enrolment visit) or
- treated with Androgen Deprivation Therapy for the first time within 6 months prior to the enrolment visit, or
- to be treated with Androgen Deprivation Therapy for the first time within 1 month after the enrolment visit
Age in the registry: 45 years to - · Sex: Male · Does not accept healthy volunteers
Sites (61)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Royal Adelaide Hospital Coordinator of this site? Confirm its status | Adelaide | Australia | Unknown status |
| Flinders Medical center Coordinator of this site? Confirm its status | Adelaide | Australia | Unknown status |
| Westmead Hospital Coordinator of this site? Confirm its status | Westmead | Australia | Unknown status |
| Hospital Municipal de Barueri Coordinator of this site? Confirm its status | Barueri | Brazil | Unknown status |
| Hospital Felicio Rocho Coordinator of this site? Confirm its status | Belo Horizonte | Brazil | Unknown status |
| Faculdade de Medicina da Universidade Estadual Paulista - Campus de Botucatu - UNESP Coordinator of this site? Confirm its status | Botucatu | Brazil | Unknown status |
| Hospital Universitário São Francisco na Providência de Deus Coordinator of this site? Confirm its status | Bragança Paulista | Brazil | Unknown status |
| Centro de Pesquisa Clínica do Brasil Coordinator of this site? Confirm its status | Brasília | Brazil | Unknown status |
| Sociedade Hospitalar Angelina Caron Coordinator of this site? Confirm its status | Campina Grande do Sul | Brazil | Unknown status |
| Nucleo de Pesquisa Clinica Hospital do Rocio Coordinator of this site? Confirm its status | Campo Largo | Brazil | Unknown status |
| Centro Médico São Francisco Coordinator of this site? Confirm its status | Curitiba | Brazil | Unknown status |
| Hospital de Caridade de Ijui Coordinator of this site? Confirm its status | Ijuí | Brazil | Unknown status |
| Fundacao Doutor Amaral Carvalho Coordinator of this site? Confirm its status | Jaú | Brazil | Unknown status |
| Hospital de Clinicas de Porto Alegre Coordinator of this site? Confirm its status | Porto Alegre | Brazil | Unknown status |
| Hospital Mae de Deus Coordinator of this site? Confirm its status | Porto Alegre | Brazil | Unknown status |
| Irmandade Da Santa Casa de Misericordia de Porto Alegre Coordinator of this site? Confirm its status | Porto Alegre | Brazil | Unknown status |
| Instituto de Medicina Integral Prof. Fernando Figueira (IMIP) Coordinator of this site? Confirm its status | Recife | Brazil | Unknown status |
| Instituto Nacional de Cardiologia Coordinator of this site? Confirm its status | Rio de Janeiro | Brazil | Unknown status |
| Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Coordinator of this site? Confirm its status | São José do Rio Preto | Brazil | Unknown status |
| Santa Casa de São Paulo (IPITEC) Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
| Hospital Santa Marcelina Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
| Instituto D'or de Pesquisa e Ensino Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
| Núcleo de Pesquisa e Ensino da Rede São Camilo Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
| Beneficência Nipo-Brasileira de São Paulo. Hospital Nipo-Brasileiro Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
| Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo and Fundação Zerbini (Incor) Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
| Hospital Alemão Oswaldo Cruz Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
| Universidade Federal do Triângulo Mineiro Coordinator of this site? Confirm its status | Uberaba | Brazil | Unknown status |
| Integral Pesquisa e Ensino Coordinator of this site? Confirm its status | Votuporanga | Brazil | Unknown status |
| Juravinski Cancer Centre Coordinator of this site? Confirm its status | Hamilton | Canada | Unknown status |
| St. Joseph's Healthcare Coordinator of this site? Confirm its status | Hamilton | Canada | Unknown status |
| Queen's University Coordinator of this site? Confirm its status | Kingston | Canada | Unknown status |
| Grand River Hospital, Grand River Regional Cancer Centre Coordinator of this site? Confirm its status | Kitchener | Canada | Unknown status |
| London Health Sciences Centre Coordinator of this site? Confirm its status | London | Canada | Unknown status |
| London Health Sciences, Victoria Hospital Coordinator of this site? Confirm its status | London | Canada | Unknown status |
| McGill University Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| Hôpital Maisonneuve-Rosemont Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| Jewish General Hospital Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| University Hospital of Montreal Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| Niagara Health, St. Catharines Site Coordinator of this site? Confirm its status | Niagara | Canada | Unknown status |
| Ottawa Hospital Research Institute Coordinator of this site? Confirm its status | Ottawa | Canada | Unknown status |
| Laval University Coordinator of this site? Confirm its status | Québec | Canada | Unknown status |
| Centre Universitaire de Sherbrooke Coordinator of this site? Confirm its status | Sherbrooke | Canada | Unknown status |
| University Health Network - Princess Margaret Cancer Centre Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
| Sunnybrook Health Sciences Centre Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
| Vancouver General Hospital Coordinator of this site? Confirm its status | Vancouver | Canada | Unknown status |
| Hospital Universitario San Ignacio Coordinator of this site? Confirm its status | Bogotá | Colombia | Unknown status |
| Fundacio Valle de Lili Coordinator of this site? Confirm its status | Cali | Colombia | Unknown status |
| FOSCAL Coordinator of this site? Confirm its status | Floridablanca | Colombia | Unknown status |
| Heart Institute - Holon Medical Center Coordinator of this site? Confirm its status | Holon | Israel | Unknown status |
| Rabin Medical Center Coordinator of this site? Confirm its status | Petah Tikva | Israel | Unknown status |
| Tel Aviv Sourasky Medical Centre Coordinator of this site? Confirm its status | Tel Aviv | Israel | Unknown status |
| St. John's Medical College and Hospital Coordinator of this site? Confirm its status | Bangalore | India | Unknown status |
| Sri shanakara cancer Hospital and Research Centre Coordinator of this site? Confirm its status | Bengaluru | India | Unknown status |
| Kamineni Academy of Medical Sciences and Research Centre Coordinator of this site? Confirm its status | Hyderabad | India | Unknown status |
| Sri Ram Cancer & Superspeciality Centre, Mahatma Gandhi Hospital Coordinator of this site? Confirm its status | Sītāpura | India | Unknown status |
| National University Hospital Coordinator of this site? Confirm its status | Singapore | Singapore | Unknown status |
| Georgia Cancer Center at Augusta University Coordinator of this site? Confirm its status | Augusta | United States | Unknown status |
| UT Southwestern Medical Center Coordinator of this site? Confirm its status | Dallas | United States | Unknown status |
| University of Kansas Medical Center Coordinator of this site? Confirm its status | Kansas City | United States | Unknown status |
| University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Istanbul University Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.