NCT03129490Active, not recruitingPhase 4
The Danish Non-vitamin K Antagonist Oral Anticoagulation Study in Patients With Atrial Fibrillation
The Danish Non-vitamin K Antagonist Oral Anticoagulation Study. A Cluster Randomized Study Comparing Safety and Efficacy of Edoxaban, Apixaban, Rivaroxaban and Dabigatran for Oral Anticoagulation in Atrial Fibrillation (DANNOAC-AF).
Source: ClinicalTrials.gov · Last updated 18 May 2025
Brief summary (registry, in English)
No randomized head-to-head comparison between the individual Non-vitamin K Antagonist Oral Anticoagulants (NOAC) exists. The DANNOAC-AF study is a nationwide cluster randomized cross-over study comparing efficacy and safety of the four NOACs, edoxaban, apixaban, rivaroxaban and dabigatran for oral anticoagulation in atrial fibrillation and atrial flutter across Danish hospitals and cardiology clinics.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 11000 (estimated)
- First submitted
- 18 Apr 2017
- Start date
- 1 Apr 2023
- Primary completion date
- 30 Oct 2027
- Lead sponsor
- Herlev and Gentofte Hospital
- Diseases
- Atrial fibrillation
- NCT number
- NCT03129490
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 11000
- From 1 Apr 2023 to the primary completion date, 30 Oct 2027
- 38 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- A prescription of a NOAC within 90 days prior to hospitalization or outpatient clinic visit for atrial fibrillation or atrial flutter.
Who the study is looking for
- A diagnosis of atrial fibrillation or atrial flutter in outpatient clinic or as discharge diagnosis after hospitalization.
- A claimed prescription of a NOAC from a Danish pharmacy within 14 days of discharge or outpatient clinic visit.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (38)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hjerteklinik Nordjylland Coordinator of this site? Confirm its status | Aalborg | Denmark | Unknown status |
| Aarhus University Hospital Coordinator of this site? Confirm its status | Aarhus | Denmark | Unknown status |
| Hjertelægerne i Ballerup Coordinator of this site? Confirm its status | Ballerup Municipality | Denmark | Unknown status |
| Hjerteklinikken Amaliegade Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Hjerteklinikken ved Speciallæge Anders Galløe Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Rigshospitalet Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Hjertelæge Christian Lange Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Bispebjerg Hospital - Department of Geriatrics Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Bispebjerg Hospital - Department of Neurology Coordinator of this site? Confirm its status | Copenhagen NV | Denmark | Unknown status |
| Hjerteklinik Østerbro I/S Coordinator of this site? Confirm its status | Copenhagen Ø | Denmark | Unknown status |
| Amager Hospital Coordinator of this site? Confirm its status | Copenhagen S | Denmark | Unknown status |
| Esbjerg Hospital Coordinator of this site? Confirm its status | Esbjerg | Denmark | Unknown status |
| Bispebjerg and Frederiksberg Hospital - Department of Cardiology Coordinator of this site? Confirm its status | Frederiksberg | Denmark | Unknown status |
| Frederiksberg Hjerteklinik Coordinator of this site? Confirm its status | Frederiksberg | Denmark | Unknown status |
| Nordsjællands Hospital - Frederiksund Coordinator of this site? Confirm its status | Frederikssund | Denmark | Unknown status |
| Gentofte Hospital Coordinator of this site? Confirm its status | Gentofte Municipality | Denmark | Unknown status |
| Glostrup Hospital - Department of Emergency Medicine Coordinator of this site? Confirm its status | Glostrup Municipality | Denmark | Unknown status |
| Glostrup Hospital - Department of Medicine / Cardiology Coordinator of this site? Confirm its status | Glostrup Municipality | Denmark | Unknown status |
| Glostrup Hospital - Department of Neurology Coordinator of this site? Confirm its status | Glostrup Municipality | Denmark | Unknown status |
| Herlev-Gentofte Hospital - Department of Medicine Coordinator of this site? Confirm its status | Herlev | Denmark | Unknown status |
| Nordsjællands Hospital Hillerød Coordinator of this site? Confirm its status | Hillerød | Denmark | Unknown status |
| Hjertelægerne i Hillerød Coordinator of this site? Confirm its status | Hillerød | Denmark | Unknown status |
| Hjørring Hospital Coordinator of this site? Confirm its status | Hjørring | Denmark | Unknown status |
| Holbæk Hospital Coordinator of this site? Confirm its status | Holbæk | Denmark | Unknown status |
| Speciallæge Michael Dilou Jacobsen Coordinator of this site? Confirm its status | Holte | Denmark | Unknown status |
| Hvidovre Hospital Coordinator of this site? Confirm its status | Hvidovre | Denmark | Unknown status |
| Næstved Hospital Coordinator of this site? Confirm its status | Næstved | Denmark | Unknown status |
| Odense University Hospital - Department of Geriatrics Coordinator of this site? Confirm its status | Odense | Denmark | Unknown status |
| Odense University Hospital - Department of Cardiology Coordinator of this site? Confirm its status | Odense | Denmark | Unknown status |
| Odense University Hospital - Department of Neurology Coordinator of this site? Confirm its status | Odense | Denmark | Unknown status |
| Odense University Hospital - Department of Emergency Medicine Coordinator of this site? Confirm its status | Odense | Denmark | Unknown status |
| Bornholms Hospital Coordinator of this site? Confirm its status | Rønne | Denmark | Unknown status |
| Zealand University Hospital - Department of Neurology Coordinator of this site? Confirm its status | Roskilde | Denmark | Unknown status |
| Zealand University Hospital, Roskilde, Department of Cardiology Coordinator of this site? Confirm its status | Roskilde | Denmark | Unknown status |
| Slagelse Hospital Coordinator of this site? Confirm its status | Slagelse | Denmark | Unknown status |
| Odense University Hospital Svendborg Coordinator of this site? Confirm its status | Svendborg | Denmark | Unknown status |
| Klinik Hjertesund Coordinator of this site? Confirm its status | Taastrup | Denmark | Unknown status |
| Vejle Hospital Coordinator of this site? Confirm its status | Vejle | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.