NCT03133156Completed
Exercise Regulation of Human Adipose Tissue
Source: ClinicalTrials.gov · Last updated 14 Aug 2025
Brief summary (registry, in English)
The purpose of this study is to determine whether exercise training leads to changes in the white adipose tissue that are beneficial to the body's regulation of sugar and body weight.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 93 (actual)
- First submitted
- 22 Feb 2017
- Start date
- 15 Jun 2017
- Primary completion date
- 17 Jan 2024
- Lead sponsor
- Joslin Diabetes Center
- Diseases
- Obesity, Type 2 diabetes
- NCT number
- NCT03133156
What you commit to
- Study type: Interventional
- Participants enrolled: 93
- From 15 Jun 2017 to the primary completion date, 17 Jan 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Type 1 Diabetes
- Heart or lung disease
- Acute systemic infection accompanied by fever, body aches, or swollen lymph glands
- Known history of HIV/AIDS or certain cancers
- Biochemical evidence of renal or hepatic dysfunction; renal or liver disease
- Demyelinating diseases such as multiple sclerosis or amyotrophic lateral sclerosis
- Clinical history of stroke
- Severe hypertension (systolic \> 160 mmHg or diastolic \> 90 mmHg)
- Inability to exercise at 50% of predicted heart rate (HR) reserve at baseline
- Participants who screen positive for The American Heart Association's contraindications to exercise testing
- History of keloid formation
Lab values
- HbA1c ≥ 9.0%
Age
- Age \<25 and \>55 years old
Other
- Basal-Bolus Insulin regimen
- Use of beta-blockers or thiazolidinediones
- BMI ≥ 37 kg/m2
- Current dieting or weight loss efforts
- Current pregnant or breastfeeding
- Recent blood donation
Who the study is looking for
- Age: 25-55 years old at the time of screening
- Body mass index (BMI) must be:
- ≥20 and ≤ 27 kg/m2 for lean subjects
- ≥25 and ≤ 37 kg/m2 for subjects with type 2 diabetes
- ≥27 and ≤ 37 kg/m2 for obese/overweight subjects
- HbA1c values:
- ≤5.7 ± 0.1% for lean and overweight/obese subjects
- 6.5 ± 0.1% - 9.0 ± 0.1% for subjects with type 2 diabetes
Age in the registry: 25 years to 55 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Joslin Diabetes Center Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.