NCT03148210Completed
Undiagnosed COPD and Asthma Population Study (UCAP)
A Randomized, Controlled, Clinical Trial to Address the Burden of Undiagnosed Airflow Obstruction in Canadian Adults
Source: ClinicalTrials.gov · Last updated 7 Mar 2024
Brief summary (registry, in English)
Previous population health studies suggest that up to 10% of Canadian adults have undiagnosed asthma or COPD- these people are currently undiagnosed and untreated, even though they may have significant respiratory symptoms. Our study will use targeted casefinding to find people with undiagnosed asthma and COPD in Canadian communities. The investigators will assess their symptoms and their health care use and number of sick days to determine the burden of undiagnosed respiratory disease in these people. The investigators will then determine whether early treatment of previously undiagnosed airflow obstruction will improve patients' health outcomes.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 508 (actual)
- First submitted
- 8 May 2017
- Start date
- 5 Jun 2017
- Primary completion date
- 9 Jan 2024
- Lead sponsor
- Ottawa Hospital Research Institute
- NCT number
- NCT03148210
What you commit to
- Study type: Interventional
- Participants enrolled: 508
- From 5 Jun 2017 to the primary completion date, 9 Jan 2024
- 15 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Subjects who report a previous physician diagnosis of asthma.
- Subjects who report a previous physician diagnosis of COPD
Other illness
- Subjects with any of the following conditions within the past 3 months: Heart attack or hospitalization for other heart problems; Stroke; Aortic or cerebral aneurysm; Detached retina or eye surgery
Other
- Subjects who are in the third trimester of pregnancy
- Subjects involved in another interventional trial
Who the study is looking for
- Subjects at least 18 years old;
- Subjects who score \> or = to 6 points on The Asthma Screening Questionnaire or \> 19.5 points on The COPD Diagnostic Questionnaire;
- Subjects who have given written informed consent to participate in this trial in accordance with local regulations;
- Subjects able to perform pre and post bronchodilator spirometry to measure lung function;
- Additional Inclusion Criteria for RCT:
- Those subjects who have undiagnosed airflow obstruction (i.e. Asthma will be diagnosed in subjects with airflow obstruction whose FEV1 improves by \> 12% and 200 ml after bronchodilator and COPD will be diagnosed in subjects who do not have a significant bronchodilator response and who exhibit persistent airflow obstruction post bronchodilator) will be asked to consent and participate in the RCT.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (15)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Of Calgary Coordinator of this site? Confirm its status | Calgary | Canada | Unknown status |
| University of Alberta Coordinator of this site? Confirm its status | Edmonton | Canada | Unknown status |
| Queen Elizabeth II, Health Sciences Centre Coordinator of this site? Confirm its status | Halifax | Canada | Unknown status |
| Firestone Institute for Respiratory Health Coordinator of this site? Confirm its status | Hamilton | Canada | Unknown status |
| Kingston General Hospital Coordinator of this site? Confirm its status | Kingston | Canada | Unknown status |
| London Health Sciences Centre Coordinator of this site? Confirm its status | London | Canada | Unknown status |
| The Research Institute of the McGill University Health Centre (RI-MUHC) Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| Hopital du Scaré-Coeur Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| The Ottawa Hospital - General Campus Coordinator of this site? Confirm its status | Ottawa | Canada | Unknown status |
| IUCP, Hôpital Laval Coordinator of this site? Confirm its status | Québec | Canada | Unknown status |
| University of Saskatchewan Coordinator of this site? Confirm its status | Saskatoon | Canada | Unknown status |
| St. Clare's Mercy Hospital Coordinator of this site? Confirm its status | St. John's | Canada | Unknown status |
| St-Micheal's Hospital Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
| Vancouver General Hospital- The Lung Centre Coordinator of this site? Confirm its status | Vancouver | Canada | Unknown status |
| St. Boniface General Hospital Coordinator of this site? Confirm its status | Winnipeg | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.