NCT03158818Completed
Chronic Hepatitis B Virus Infection in Zambia
Chronic Hepatitis B Virus Infection in Zambia: a Prospective Clinical Cohort Study
Source: ClinicalTrials.gov · Last updated 12 Jun 2026
Brief summary (registry, in English)
Chronic hepatitis B virus infection is a common condition in Zambia. Among Zambian blood donors, up to 8% are chronically infected with HBV. Despite the burden, awareness of HBV is low in Zambia and the Ministry of Health is in early stages of development of guidelines for HBV screening, treatment, and prevention. The purpose of this clinical cohort study is to characterize the clinical features of chronic HBV infection at UTH and describe treatment and care outcomes. The investigators will enroll 500 adults and follow the cohort for up to 5 years to assess short and long-term viral, serologic, and liver outcomes such as cirrhosis and liver cancer.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 326 (actual)
- First submitted
- 8 May 2017
- Start date
- 23 Aug 2016
- Primary completion date
- 20 Nov 2024
- Lead sponsor
- University of Alabama at Birmingham
- NCT number
- NCT03158818
What you commit to
- Study type: Observational
- Participants enrolled: 326
- From 23 Aug 2016 to the primary completion date, 20 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- HIV-positive
Other
- Unable or unwilling to provide informed consent
Who the study is looking for
- Age 18 years or older
- HBV-infected, defined as any single positive HBsAg assay
Age in the registry: 18 years to 99 years · Sex: All
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tropical Gastroenterology and Nutrition Group Coordinator of this site? Confirm its status | Lusaka | Zambia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.