NCT03170453Completed
Confirmatory Efficacy Trial of Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder
Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder
Source: ClinicalTrials.gov · Last updated 9 Jan 2025
Brief summary (registry, in English)
This study will investigate and confirm the efficacy of two psychological treatments for adults with autism spectrum disorder. Cognitive Enhancement Therapy (CET) is a cognitive remediation intervention that aims to help adults with problems in thinking, planning, and socialization. Enriched Supportive Therapy (EST) is an individual supportive therapy that aims to help adults learn about their condition, manage their emotions and stress, improve their social skills, and cope with everyday problems.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 86 (actual)
- First submitted
- 27 Feb 2017
- Start date
- 1 Jun 2015
- Primary completion date
- 4 May 2022
- Lead sponsor
- University of Pittsburgh
- Diseases
- Autism
- NCT number
- NCT03170453
What you commit to
- Study type: Interventional
- Participants enrolled: 86
- From 1 Jun 2015 to the primary completion date, 4 May 2022
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Organic brain syndrome
- History of substance abuse or dependence within the past 3 months
- Comorbid attention deficit hyperactivity disorder (ADHD) that is untreated
- Comorbid personality disorder
- History of disruptive or violent behavior
Other
- IQ \< 80
- English language skills below a sixth grade level
- Persistent suicidal or homicidal behavior
- Any magnetic resonance imaging contraindications
Who the study is looking for
- Age 16-45 years
- Diagnosis of autism, Asperger's syndrome, or pervasive developmental disorder not otherwise specified (NOS) verified by the autism diagnostic observation schedule (ADOS) or autism diagnostic interview-revised (ADI-R)
- Presence of significant social and cognitive disability, based on the Cognitive Style and Social Cognition Eligibility Interview (Hogarty et al., 2004)
- Intelligence quotient (IQ) greater than 80
- Ability to read and speak fluent English
- Availability of a family member or close friend allowed to provide information on the participant
- Ability to attend weekly treatment sessions in Pittsburgh, PA
Age in the registry: 16 years to 45 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Pittsburgh Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.