NCT03187951Active, not recruiting
PancFit: Multimodal Exercise During Preoperative Therapy for Pancreatic Cancer
PancFit: Multimodal Exercise During Preoperative Therapy for Pancreatic Cancer: A Randomized Trial Testing Effects on Fitness, Health-Related Quality of Life, and Tumor Vasculature
Source: ClinicalTrials.gov · Last updated 20 May 2026
Brief summary (registry, in English)
Any time the words "you," "your," "I," or "me" appear, it is meant to apply to the potential participant. The goal of this clinical research study is to learn if regular exercise and behavioral skills training can help to improve physical activity in patients with pancreatic cancer who are scheduled to receive chemotherapy and/or radiation before standard-of-care surgery. This is an investigational study. Up to 128 participants will be enrolled on this study. All will take part at MD Anderson.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 152 (actual)
- First submitted
- 13 Jun 2017
- Start date
- 13 Jun 2017
- Primary completion date
- 31 Dec 2022
- Lead sponsor
- M.D. Anderson Cancer Center
- Diseases
- Pancreatic cancer
- NCT number
- NCT03187951
What you commit to
- Study type: Interventional
- Participants enrolled: 152
- From 13 Jun 2017 to the primary completion date, 31 Dec 2022
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recurrent cancer following prior resection
- Completed preoperative therapy and are on their presurgical rest period.
Other illness
- Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease (New York Heart Association functional class III or IV)
- Myopathic or rheumatologic disease that impacts physical function
- Neuroendocrine cancer
Other
- Non-English speaking
- Unable to complete the baseline assessment questionnaires or functional assessments
- Recent fracture or acute musculoskeletal injury that precludes the ability to weight bear fully on all 4 limbs in order to participate in an exercise intervention
- Numeric pain rating scale of \>/= 7 out of 10
Who the study is looking for
- Pancreatic cancer of any type, biopsy-proven
- Scheduled to receive preoperative therapy (chemotherapy, radiation or chemoradiation) either on- or off-protocol.
- Anticipated to undergo pancreatectomy in \>/= 6 weeks from enrollment
- Able to understand the description of the study and willing to participate
- Able to understand the exercise program
- Able to maintain daily exercise logs
- Telephone or email access and agreement to engage with the research personnel via phone or email
- Meet all screening requirements.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Texas - MD Anderson Cancer Center Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.