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NCT03189420Active, not recruiting

Glioma Microenvironment an Exploratory Study

Source: ClinicalTrials.gov · Last updated 19 Apr 2024

Brief summary (registry, in English)

Diffuse glioms are primary brain tumors characterized by infiltrative growth and high heterogeneity, which render the disease mostly incurable. Advances in genetic analysis revealed that molecular and epigenetic alterations predict patients´s overall survival and clinical outcome. However, glioma tumorigenicity is not exclusively caused by its genetic alterations. The crosstalk between tumor cells and the surrounding microenvironment plays a crucial role in modulating glioma growth and aggressiveness. In this sense, to understand the tumor microenvironment would elucidate potential treatment alternatives. The focus will be to evaluate myeloid cells and cytokines levels.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
30 (estimated)
First submitted
14 Jun 2017
Start date
1 Oct 2016
Primary completion date
31 Oct 2025
Lead sponsor
Hospital Sirio-Libanes
Diseases
Glioblastoma
NCT number
NCT03189420

What you commit to

  • Study type: Observational
  • Planned participants: 30
  • From 1 Oct 2016 to the primary completion date, 31 Oct 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Chronic neurodegenerative and inflamatory diseases

Who the study is looking for

  • 18 - 65 years old with brain tumor
  • Patients that will be submitted to brain tumor ressection

Age in the registry: 18 years to 65 years · Sex: All

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Hospital Sirio Libanes
Coordinator of this site? Confirm its status
São PauloBrazilUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.