NCT03190525Active, not recruiting
Clinical Decision-making, Prognosis, Quality of Life and Satisfaction in Relapsed/Refractory Multiple Myeloma
CLinical Decision-making, Prognosis, quAlity of Life and Satisfaction With caRe in patIents With Relapsed/refracTory Multiple mYeloma (CLARITY)
Source: ClinicalTrials.gov · Last updated 12 Jun 2025
Brief summary (registry, in English)
The primary objective is overall survival (OS) as predicted by baseline self-reported EORTC QLQ-C30 (European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30) fatigue scale ratings, independently from other prognostic factors for OS in multiple myeloma (MM), including the clinically-based prognostic frailty score.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 530 (estimated)
- First submitted
- 12 Jun 2017
- Start date
- 13 Nov 2017
- Primary completion date
- 31 Dec 2025
- Lead sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
- Diseases
- Multiple myeloma
- NCT number
- NCT03190525
What you commit to
- Study type: Observational
- Planned participants: 530
- From 13 Nov 2017 to the primary completion date, 31 Dec 2025
- 35 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Having reported any grade ≥3 adverse event within two weeks prior to study entry.
- Having received more than 5 lines of therapies.
Other illness
- Having any kind of psychiatric disorder or major cognitive dysfunction hampering the provision of informed consent.
Who the study is looking for
- MM patients who have received at least 1 prior line of therapy and are considered as RRMM according to IMWG criteria.
- Adult patients (≥ 18 years old).
- Written informed consent provided.
- Patients who have been enrolled onto other study therapy protocols are also eligible.
- Having a full baseline PRO evaluation completed.
- All data a available to calculate the frailty score.
Age in the registry: 18 years to - · Sex: All
Sites (35)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| London North West Healthcare Trust Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Azienda Ospedaliero Universitaria Ospedali Riuniti Umberto I G M Lancisi G Salesi Coordinator of this site? Confirm its status | Ancona | Italy | Unknown status |
| S. Orsola Malpighi Coordinator of this site? Confirm its status | Bologna | Italy | Unknown status |
| Divisione di Ematologia Ospedale A. Perrino Coordinator of this site? Confirm its status | Brindisi | Italy | Unknown status |
| ASL N.8 - Ospedale "A. Businco" - Struttura Complessa di Ematologia e CTMO Coordinator of this site? Confirm its status | Cagliari | Italy | Unknown status |
| Università di Catania - Cattedra di Ematologia - Ospedale "Ferrarotto" Coordinator of this site? Confirm its status | Catania | Italy | Unknown status |
| Unità di Onco-Ematologia - Azienda Ospedaliera - Garibaldi Coordinator of this site? Confirm its status | Catania | Italy | Unknown status |
| Unità Operativa Oncologia Medica - A.O. Pugliese Ciaccio Coordinator of this site? Confirm its status | Catanzaro | Italy | Unknown status |
| Azienda Ospedaliero Universitaria Arcispedale Sant'Anna Dipartimento di Scienze Mediche Sezione di Ematologia e Fisiopatologia dell'Emostasi Coordinator of this site? Confirm its status | Cona | Italy | Unknown status |
| U.O. Ematologia - P.O. Annunziata - A.O. di Cosenza Coordinator of this site? Confirm its status | Cosenza | Italy | Unknown status |
| Unità di Ricerca e di Malattie del sangue - Ematologia San Luca Vecchio Pad. 16 - 1° Piano Coordinator of this site? Confirm its status | Florence | Italy | Unknown status |
| ASL Le/1 P.O. Vito Fazzi - U.O. di Ematologia ed UTIE Coordinator of this site? Confirm its status | Lecce | Italy | Unknown status |
| Azienda Ospedaliera Universitaria - Policlinico G. Martino Dipartimento di Medicina Interna - U.O. Messina Coordinator of this site? Confirm its status | Messina | Italy | Unknown status |
| U.O. Ematologia - P.O. Annunziata - A.O. di Cosenza Coordinator of this site? Confirm its status | Messina | Italy | Unknown status |
| UO Ematologia - AOU Policlinico di Modena Coordinator of this site? Confirm its status | Modena | Italy | Unknown status |
| S.C.D.U. Ematologia - DIMECS e Dipartimento Oncologico - Università del Piemonte Orientale Amedeo Avogadro Coordinator of this site? Confirm its status | Novara | Italy | Unknown status |
| U.O. di Oncoematologia -plesso ospedaliero "A. Tortora" di Pagani Coordinator of this site? Confirm its status | Pagani | Italy | Unknown status |
| U.O. di Ematologia con trapianto - Centro di Riferimento Regionale per le coagulopatie rare nel bambino e nell'adulto Dipart. Biomedico di Medicina Interna - A.U. Policlinico "Paolo Giaccone" Coordinator of this site? Confirm its status | Palermo | Italy | Unknown status |
| Day Hospital dell'U.O.C di Ematologia e CTMO Padiglione 1 TORRE DELLE MEDICINE, 6° piano Coordinator of this site? Confirm its status | Parma | Italy | Unknown status |
| UOS di Ematologia Servizio di Immunoematologia e medicina Trasfusionale Azienda Sanitaria Provinciale 7 Coordinator of this site? Confirm its status | Ragusa | Italy | Unknown status |
| Unità Operativa Complessa di Ematologia - Arcispedale S. Maria Nuova Coordinator of this site? Confirm its status | Reggio Emilia | Italy | Unknown status |
| Ospedale "Infermi" Coordinator of this site? Confirm its status | Rimini | Italy | Unknown status |
| Università degli Studi "Sapienza" - Dip Biotecnologie Cellulari ed Ematologia - Divisione di Ematologia Coordinator of this site? Confirm its status | Roma | Italy | Unknown status |
| Asl Roma 2, Ospedale S. Eugenio- Ospedale S.Eugenio - Uoc Ematologia Coordinator of this site? Confirm its status | Roma | Italy | Unknown status |
| Az. Ospedaliera "Sant' Andrea"-Università la Sapienza Seconda Facoltà di Medicina e Chirurgia Coordinator of this site? Confirm its status | Roma | Italy | Unknown status |
| Università degli Studi - Policlinico di Tor Vergata Coordinator of this site? Confirm its status | Roma | Italy | Unknown status |
| Divisione Ematologia - Università Campus Bio-Medico Coordinator of this site? Confirm its status | Roma | Italy | Unknown status |
| Unità Operativa di Oncologia - Presidio Ospedaliero N. Giannetasio - Azienda ASL 3 Coordinator of this site? Confirm its status | Rossano | Italy | Unknown status |
| Istituto di Ematologia - IRCCS Ospedale Casa Sollievo della Sofferenza Coordinator of this site? Confirm its status | San Giovanni Rotondo | Italy | Unknown status |
| Ematologia - Dipartimento di Medicina Clinica e Sperimentale Coordinator of this site? Confirm its status | Sassari | Italy | Unknown status |
| U.O.C. Ematologia - A.O. Senese - Policlinico " Le Scotte" Coordinator of this site? Confirm its status | Siena | Italy | Unknown status |
| U.O.C. di Ematolgia - A.O. " SS Annunziata" - P.O. S.G. Moscati Coordinator of this site? Confirm its status | Taranto | Italy | Unknown status |
| A.O. Santa Maria - Terni S.C Oncoematologia Coordinator of this site? Confirm its status | Terni | Italy | Unknown status |
| Divisione di Ematologia dell' Università degli Studi di Torino - "Città della Salute e della Scienza di Torino" Coordinator of this site? Confirm its status | Torino | Italy | Unknown status |
| Struttura Complessa II Medicina - Ematologia - Centro di Riferimento Ematologico - Ospedale Maggiore Coordinator of this site? Confirm its status | Trieste | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.