NCT03238690Recruiting
LVAD Conditioning for Cardiac Recovery
Sequential Left Ventricular Assist Device (LVAD) Unloading and Conditioning to Induce Sustained Cardiac Recovery
Source: ClinicalTrials.gov · Last updated 13 Aug 2026
Brief summary (registry, in English)
The purpose of this study is to investigate the potential recovery of heart function in end-stage heart failure patients supported with a Left Ventricular Assist Device (LVAD) through applying a myocardial conditioning protocol. During myocardial conditioning, LVAD speed is reduced gradually in order to increase the work load of the heart. Multiple previous studies have shown that interventions like this may improve heart function and give patients the opportunity for a better quality of life.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 31 Jul 2017
- Start date
- 23 Jun 2017
- Primary completion date
- 30 Jun 2028
- Lead sponsor
- STAVROS G DRAKOS
- Diseases
- Heart failure
- NCT number
- NCT03238690
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 23 Jun 2017 to the primary completion date, 30 Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Neither the subject nor the subject's representative is willing to provide written consent for participation
- Subjects with adverse events leading to hospitalization during the optimum unloading phase are excluded from participation in the controlled reloading phase
Who the study is looking for
- Diagnosed with heart failure undergoing LVAD implantation as a bridge to transplant
- Enrolled in the Effects of Mechanical Unloading on Myocardial Function and Structure study (IRB 30622)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Utah Coordinator of this site? Confirm its status | Salt Lake City | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.