NCT03240328RecruitingPhase 1
The Effect of Chimeric Antigen Receptor (CAR)-T Cell Therapy on the Reconstitution of HIV-specific Immune Function
The Effect of CAR-T Cell Therapy on the Reconstitution of HIV-specific Immune Function
Source: ClinicalTrials.gov · Last updated 14 Sept 2022 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
To study the safety and effectiveness of CAR-T Cell therapy on HIV patients whose plasma HIV has been successfully suppressed after cART, which is expected to enhance the res-constitution of HIV-specific immune function to assist the eradication of HIV reservoir.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 21 May 2017
- Start date
- 4 Oct 2017
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Guangzhou 8th People's Hospital
- Diseases
- HIV
- NCT number
- NCT03240328
What you commit to
- Study type: Interventional · Phase 1
- Planned participants: 40
- From 4 Oct 2017 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- With active HBV or HCV infection, or serious opportunistic infections.
- With serious chronic disease such like diabetes, the mental illness,et al
- History of suffering from pancreatitis during cART.
Other
- Pregnant or breast-fed.
- With poor adherence.
- Unable to complete follow up.
Who the study is looking for
- HIV infection confirmed.
- Receiving cART more than 12 months.
- HIV viral-load \< 50 copies/ml and CD4 cell count more than 350 cells/ul.
- Without serious liver, heart, liver and kidney diseases.
- The subjects know about the study and volunteer to attend the research and sign the informed consent.
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Guangzhou 8th People's Hospital Coordinator of this site? Confirm its status | Guangzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.