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NCT03255408RecruitingPhase 1/2

Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia

Role of Cerebral Blood Flow on Ventilatory Stability During Sleep in Normoxia and Intermittent Hypoxia

Source: ClinicalTrials.gov · Last updated 1 May 2026

Brief summary (registry, in English)

A prospective double blind, placebo-controlled, randomized cross-over trial to evaluate the effect of lowering cerebral blood flow on the ventilatory chemoreflexes (acute hypoxic and hypercapnic ventilatory responses).

Status (registry)
Recruiting
Phase (registry)
Phase 1/2
Study type
Interventional
Enrollment
12 (estimated)
First submitted
6 Aug 2017
Start date
1 Jan 2023
Primary completion date
30 Dec 2027
Lead sponsor
University of Calgary
Diseases
Stroke
NCT number
NCT03255408

What you commit to

  • Study type: Interventional · Phase 1/2
  • Planned participants: 12
  • From 1 Jan 2023 to the primary completion date, 30 Dec 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Cerebrovascular, cardio-respiratory, renal and metabolic diseases
  • Bleeding disorders and upper gastrointestinal diseases e.g. peptic ulcer disease
  • Drug allergies to non-steroidal anti-inflammatories

Other

  • Pregnancy, obese and sleep-disordered breathing
  • Currently smoking

Who the study is looking for

  • Healthy adults
  • 18 - 45 years of age
  • Living in Calgary for the past one year
  • Have no medical condition or should not be taking any blood pressure medications.
  • The participant should not be lactose intolerant

Age in the registry: 18 years to 45 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University Of Calgary
Coordinator of this site? Confirm its status
CalgaryCanadaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.