NCT03266055Active, not recruiting
Effects of Blueberry on Gut Microbiota and Metabolic Syndrome
Prebiotic Effects of Blueberry in Overweight/Obese Individuals: Potential Role of the Gut Microbiota in Alleviating the Metabolic Syndrome.
Source: ClinicalTrials.gov · Last updated 8 Sept 2026
Brief summary (registry, in English)
There is growing evidence that nutritional intervention with dietary polyphenols can positively modulate the gut microbiota to improve cardiometabolic health. Whether the beneficial effects of blueberries on obesity and the metabolic syndrome can be linked to their potential impact on the gut microbiota and intestinal integrity remains speculative at this time. Moreover, the mechanisms of action underlying health benefits associated to blueberry consumption are still unknown. The investigators are thus proposing to combine the study of metagenomics, transcriptomics and metabolomics to test whether a prebiotic activity of highbush blueberries can play a role in the prevention of obesity-linked metabolic syndrome in a clinical setting.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 59 (actual)
- First submitted
- 6 Jul 2017
- Start date
- 1 Sept 2017
- Primary completion date
- 14 Jan 2019
- Lead sponsor
- Laval University
- Diseases
- Obesity
- NCT number
- NCT03266055
What you commit to
- Study type: Interventional
- Participants enrolled: 59
- From 1 Sept 2017 to the primary completion date, 14 Jan 2019
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Regular use of medication affecting study parameters
- Surgery in the last 3 months or planed during the study
Other illness
- Metabolic disorders (hypertension, diabetes, hypercholesterolemia)
- Allergy or intolerance for blueberries
Other
- Use of natural health product in the last 3 months
- Use of antibiotics in the last 3 months
- Nicotine users
- Blueberry taste aversion
- More than 2 alcohol drinks par day
- Particular dietary habits (vegetarism, gluten-free diet, cetogenic diet...)
- Weight change of more than 5% in the last 3 months
Who the study is looking for
- Men and premenopause women in good health
- Caucasians
- At least one of the following : BMI between 25 and 40 kg/m2 or Waist circumference ≥ 80 cm for women and ≥ 94 cm for men
- At least one of the following : TG ≥ 1.35 mmol/L or fasting insulinemia ≥ 42 pmol/L
Age in the registry: 18 years to 55 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Laval University Coordinator of this site? Confirm its status | Québec | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.