NCT03268109Completed
COGnitive ImpairmenT in Older HIV-infected Patients ≥ 65 Years Old
COGnitive ImpairmenT in Older HIV-infected Patients ≥ 65 Years Old.
Source: ClinicalTrials.gov · Last updated 25 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Despite combined antiretroviral therapy (cART), milder forms of HIV-associated neurocognitive disorders (HAND) persist in 20-50% of persons living with HIV (PLHIV). Since more PLH are at risk for HAND due to aging, the frequency of HAND in PLHIV ≥ 65 years old is important to quantify for planning early intervention to attenuate both functional and occupational disabilities due to cognitive impairment.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 281 (actual)
- First submitted
- 29 Aug 2017
- Start date
- 22 Sept 2017
- Primary completion date
- 12 May 2025
- Lead sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
- Diseases
- HIV
- NCT number
- NCT03268109
What you commit to
- Study type: Observational
- Participants enrolled: 281
- From 22 Sept 2017 to the primary completion date, 12 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Opportunistic infection \< 5 years
Other
- Contraindications to MRI
Who the study is looking for
- Personal or familial cognitive complaints
- Individual aged ≥ 65 years old and \< 81 years old
- Instrumental activities of daily living (IADL) score between 3-4
- French speaking individual
- Informed consent signed For PLHIV
- HIV infection
- Undetectable HIV viral load ≥ 1 year
- Current cluster of differentiation (CD4) cell count \> 100/mm3 For controls
- negative HIV serology ≤ 6 months
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fondation Ophtalmologique A. de Rothschild /URC Coordinator of this site? Confirm its status | Paris | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.