NCT03296826Recruiting
Prospective Cohort Study of Germline Variant Carriers With BRCA1 or BRCA2
Source: ClinicalTrials.gov · Last updated 3 Feb 2026
Brief summary (registry, in English)
To determine the incidence and risk factors in the development of ovarian, fallopian tube, and peritoneal cancers in Japanese women carrying Breast Cancer Susceptibility Gene (BRCA)1/2 variants.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 600 (estimated)
- First submitted
- 25 Sept 2017
- Start date
- 8 Nov 2017
- Primary completion date
- 31 Mar 2032
- Lead sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
- Diseases
- Ovarian cancer
- NCT number
- NCT03296826
What you commit to
- Study type: Observational
- Planned participants: 600
- From 8 Nov 2017 to the primary completion date, 31 Mar 2032
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Women previously diagnosed with ovarian, fallopian tube, or peritoneal cancer, and not excluding those with a personal history of breast cancer development.
Other illness
- Women without ovarian or fallopian tube cancer at the time of informed consent.
Other
- Other individuals considered inappropriate for involvement in this study by the investigator.
Who the study is looking for
- Women carrying BRCA1/2 variants (those with either BRCA1 or BRCA2 variants, or those carrying both variants) and women carrying a variant of uncertain significance (VUS).
- Women who have received sufficient genetic counseling at any medical institution, prior to enrollment to the study.
- Women who provide consent should be 20 years of age or older.
- Women who provide written consent.
Age in the registry: 20 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Okayama University Coordinator of this site? Confirm its status | Okayama | Japan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.