NCT03298243Recruiting
Use of Sensory Substitution to Improve Arm Control After Stroke
Augmenting Kinesthetic Feedback to Improve Hemiparetic Arm Control After Stroke
Source: ClinicalTrials.gov · Last updated 29 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Supplementing or augmenting sensory information to those who have lost proprioception after stroke could help improve functional control of the arm. Thirty subjects will be recruited to a single site to evaluate the ability of supplemental kinesthetic feedback (a form of vibrotactile stimulation) to improve motor function. Participants will be tested in performing reaching movements as well as more functional tasks such as simulated drinking from a glass
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 22 Sept 2017
- Start date
- 17 Jul 2023
- Primary completion date
- 31 May 2026
- Lead sponsor
- Marquette University
- Diseases
- Stroke
- NCT number
- NCT03298243
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 17 Jul 2023 to the primary completion date, 31 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- subjects who are currently using or under the influence of aminoglycoside antibiotics, curare-like agents, or other agents that may interfere with neuromuscular function.
- concurrent illness limiting the capacity to conform to study requirements.
Other illness
- subjects with a bleeding disorder.
- subjects with fixed contractures or a history of tendon transfer in the involved limb.
- subjects with a diagnosis of myasthenia gravis, amyotrophic lateral sclerosis or any disease that might interfere with neuromuscular function.
- subjects with a history of epilepsy.
- history of other psychiatric co-morbidities (e.g. schizophrenia).
- malignant or benign intra-axial neoplasms.
- Cardiac pacemaker, cardiac arrhythmia or history of significant cardiovascular or respiratory compromise.
- subjects with a systemic infection.
Other
- Inability of subjects to give informed consent or follow two-stage instructions.
- subjects with profound atrophy or excessive weakness of muscles in the target area(s) of testing.
Who the study is looking for
- stroke survivors who can perform our stabilization and grip modulation tasks and who
- had a single ischemic or hemorrhagic stroke of the middle cerebral artery (MCA) in the chronic state of recovery (\> 6 months post-stroke).
- ability to give informed consent and be able to follow two-stage instructions.
- mild-to-moderate motor impairment as assessed using the upper extremity (UE) portion of the Fugl-Meyer Motor Assessment (FM); i.e., UE-FM score between 28 and 50 (inclusive) out of a possible 66.
- proprioceptive deficit at the elbow in the more involved (contralesional) arm.
- preserved tactile sensation in either the ipsilesional arm and/or thigh.
- a minimal active wrist extension of 5°.
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Marquette University Coordinator of this site? Confirm its status | Milwaukee | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.