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NCT03309033Active, not recruiting

Extended Follow-up of Women Who Received One, Two, and Three Doses of the HPV Vaccine in the Costa Rica Vaccine Trial (CVT), ESCUDDO-CVT Study

Long-Term Immunologic Follow-Up of Women Who Received One, Two, and Three Doses of the Bivalent HPV Vaccine in the Costa Rica HPV-16/18 Vaccine Trial (CVT): Generating Durability Data: The ESCUDDO-CVT Study

Source: ClinicalTrials.gov · Last updated 28 Sept 2026

Brief summary (registry, in English)

This study is extending follow up of women who participated in the Costa Rica Vaccine Trial (CVT) and received one dose or two doses of the human papillomavirus (HPV) vaccine, along with a group of women who received three doses. It also studies the stability of HPV defenses in these groups of women for up to 20 years after initial vaccination. Studying samples of blood in the laboratory may provide information on how long one, two, and three doses of the vaccine provide protection against HPV. The results of this study may also help researchers learn whether one dose of HPV vaccine is enough to protect against HPV.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
946 (actual)
First submitted
12 Oct 2017
Start date
2 Jul 2018
Primary completion date
5 Mar 2026
Lead sponsor
National Cancer Institute (NCI)
NCT number
NCT03309033

What you commit to

  • Study type: Observational
  • Participants enrolled: 946
  • From 2 Jul 2018 to the primary completion date, 5 Mar 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • A random subset of the three-dose women

Who the study is looking for

  • Participation in the CVT Long Term Follow-Up (LTFU) study

Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Agencia Costarricense de Investigaciones Biomédicas (ACIB)
Coordinator of this site? Confirm its status
LiberiaCosta RicaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.