NCT03336931Active, not recruiting
PRecISion Medicine for Children With Cancer
A Multicenter Prospective Study of the Feasibility and Clinical Value of a Diagnostic Service for Identifying Therapeutic Targets and Recommending Personalised Treatment for Children and Adolescents With High-risk Cancer
Source: ClinicalTrials.gov · Last updated 23 Apr 2024
Brief summary (registry, in English)
This is a multicentre prospective study of the feasibility and clinical value of a diagnostic service for identifying therapeutic targets and recommending personalised treatment for children and adolescents with high-risk cancer.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 550 (estimated)
- First submitted
- 22 Oct 2017
- Start date
- 5 Sept 2017
- Primary completion date
- 31 Aug 2028
- Lead sponsor
- Sydney Children's Hospitals Network
- Diseases
- Childhood cancers
- NCT number
- NCT03336931
What you commit to
- Study type: Observational
- Planned participants: 550
- From 5 Sept 2017 to the primary completion date, 31 Aug 2028
- 8 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Age ≤ 21 years
- Histologic diagnosis of high-risk malignancy defined as expected overall survival \< 30% OR where standard therapy would result in unacceptable and severe morbidity
- Appropriate tissue samples are available for analysis
- Life expectancy \> 6 weeks
- Written informed consent
Age in the registry: - to 21 years · Sex: All · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Women's and Children's Hospital Coordinator of this site? Confirm its status | Adelaide | Australia | Unknown status |
| Queensland Children's Hospital Coordinator of this site? Confirm its status | Brisbane | Australia | Unknown status |
| Royal Children's Hospital Coordinator of this site? Confirm its status | Melbourne | Australia | Unknown status |
| Monash Children's Hospital Coordinator of this site? Confirm its status | Melbourne | Australia | Unknown status |
| John Hunter Children's Hospital Coordinator of this site? Confirm its status | Newcastle | Australia | Unknown status |
| Perth Children's Hospital Coordinator of this site? Confirm its status | Perth | Australia | Unknown status |
| Sydney Children's Hospital, Randwick Coordinator of this site? Confirm its status | Sydney | Australia | Unknown status |
| The Children's Hospital at Westmead Coordinator of this site? Confirm its status | Sydney | Australia | Unknown status |
Related publications
- Family experiences of receiving treatment recommendations in a precision medicine trial for poor-prognosis childhood cancer.NPJ Genom Med · 2026 · PMID 42399266
This page is information, not medical advice. Discuss any trial with your doctor.