NCT03348280Active, not recruiting
Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics
Source: ClinicalTrials.gov · Last updated 24 Dec 2025
Brief summary (registry, in English)
This trial will evaluate whether a particular type of circulating white blood cell, monocytes, from type 2 diabetics with high blood pressure and vitamin D deficiency vs. sufficiency will induce hormones that increase blood pressure.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 40 (estimated)
- First submitted
- 23 Oct 2017
- Start date
- 1 Sept 2017
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Washington University School of Medicine
- Diseases
- High blood pressure, Type 2 diabetes
- NCT number
- NCT03348280
What you commit to
- Study type: Observational
- Planned participants: 40
- From 1 Sept 2017 to the primary completion date, 31 Dec 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent weight loss of more than 5% within 3 months prior to screening
- Previous heart attack and stroke
Other illness
- Heart failure
- Chronic renal failure: stage 4 or worse
- Chronic diseases known to affect immunity
Other
- Current Pregnancy
- Hypercalcemia
- Atrial fibrillation
- Heavy alcohol consumption
- Extreme diets (Atkins, South Beach)
- \>2 + proteinuria on urine sample
Who the study is looking for
- Type 2 diabetes (T2DM)
- Age: 25-80 years old
- Vitamin 25(OH)D3 levels \<20 or \>30 ng/ml.
- HbA1c: 5.5%-9.5%
- Blood Pressure: \<160/100 mm Hg on BP lowering medications and
- Blood Pressure: \>120/80 to 160/100 mmHg without BP lowering medications
Age in the registry: 25 years to 80 years · Sex: All
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Washington University Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
| Barnes-Jewish & Washington University Diabetes Center Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.