NCT03385902Completed
Assessment of Dialysis Initiation by a Fuzzy Mathematics Equation
Impact on Mortality of Timing of Dialysis Initiation in Patients With End-stage Renal Disease by a Novel Assessment Based on Fuzzy Mathematics
Source: ClinicalTrials.gov · Last updated 8 May 2026
Brief summary (registry, in English)
The purpose of this study is to evaluate the impact of the optimal and late initiation of dialysis on the mortality and quality of life in end-stage renal disease (ESRD) patients by the Dialysis Initiation based on Fuzzy mathematics Equation (DIFE), which is a novel equation for the assessment of timing of dialysis initiation established by Fuzzy mathematics.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 388 (actual)
- First submitted
- 21 Dec 2017
- Start date
- 14 Apr 2018
- Primary completion date
- 20 May 2024
- Lead sponsor
- The First Affiliated Hospital of Dalian Medical University
- Diseases
- Chronic kidney disease
- NCT number
- NCT03385902
What you commit to
- Study type: Interventional
- Participants enrolled: 388
- From 14 Apr 2018 to the primary completion date, 20 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Have received or planning to receive a kidney transplant or peritoneal dialysis during the study
Other illness
- Acute kidney injury (AKI) or AKI on chronic kidney disease (CKD)
- With the primary disease of systemic lupus erythematosus (SLE) or systemic vasculitis
- Has a recently diagnosed cancer that was likely to affect survival (except for the following cases: the cancer has been confirmed to be cured or relieved for over 5 years, have had the radical resection for the basal cell carcinoma or squamous carcinoma of skin or carcinoma in-situ of any part of the body )
- Positive test of Human Immunodeficiency Virus (HIV), the hepatitis B virus antigen (HBsAg) or anti-hepatitis C virus antibody (HCV Ab)
- Acute infection within 1 month
Other
- Hepatocirrhosis
- Bad habit which is difficult to withdrawal such as alcohol abuse
- Poor compliance and could not be treated according to the protocol
- Being pregnant, nursing or having a plan for pregnancy
- Life expectancy less than 1 year
- The investigator confirm that should not enroll in the study with any other cases
Who the study is looking for
- Have progressive chronic kidney disease with an eGFR less than 15 ml/min/1.73m2 and a DIFE between 30-35
- Expected to commence maintenance hemodialysis as their renal replacement treatment
- Agreeable to randomization
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital of Dalian Medical University Coordinator of this site? Confirm its status | Dalian | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.