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NCT03388788Active, not recruiting

Body Weight, Sleep, and Heart Health

Circadian Mechanisms of Cardiovascular Risk in Obesity

Source: ClinicalTrials.gov · Last updated 18 May 2026

Brief summary (registry, in English)

A multidisciplinary investigation examining the circadian mechanisms regulating cardiovascular (CV) risk, with an additional focus on obesity. Specifically, in a valid circadian protocol, the investigators aim to study resting cardiovascular risk markers and the reactivity of circadian rhythms in these risk markers to standardized stressors. It is intended to compare results in lean and obese individuals to determine if there are specific risks across the circadian cycle specific to obesity. Furthermore, using an exploratory approach, the investigators propose to explore impairment in pre/post synaptic function in the cardiac left ventricle.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
17 (actual)
First submitted
20 Dec 2017
Start date
1 May 2018
Primary completion date
30 Sept 2024
Lead sponsor
Oregon Health and Science University
Diseases
Obesity
NCT number
NCT03388788

What you commit to

  • Study type: Observational
  • Participants enrolled: 17
  • From 1 May 2018 to the primary completion date, 30 Sept 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Prior shift work within 6 months prior to the study.
  • Prescription medications
  • Drugs of abuse

Other illness

  • History of smoking/tobacco use
  • Acute, chronic, or debilitating medical condition (including diabetes, hypertension, and metabolic syndrome)

Other

  • Insomnia
  • Moderate to severe obstructive sleep apnea.

Who the study is looking for

  • Ages 25-65
  • Lean and overweight (BMI 18.5-40kg/m2)
  • Habitually sedentary

Age in the registry: 25 years to 65 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Oregon Health Science University
Coordinator of this site? Confirm its status
PortlandUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.