NCT03397602Recruiting
Exercise Training in Patients With Persistent or Permanent Atrial Fibrillation
Exercise Training in Patients With Persistent or Permanent Atrial Fibrillation - a Multi-centre Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 11 Mar 2026
Brief summary (registry, in English)
The main purpose of this project is to evaluate the effects of high-intensity interval training (HIIT) compared to moderate-intensity continuous exercise training (MICE) and standard care on exercise capacity and quality of life in patients with persistent or permanent atrial fibrillation. Positive findings are vitally important for these patients, given the condition's substantial morbidity, mortality and high economic costs.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 132 (estimated)
- First submitted
- 4 Jan 2018
- Start date
- 23 Jan 2019
- Primary completion date
- 30 Dec 2027
- Lead sponsor
- Ottawa Heart Institute Research Corporation
- Diseases
- Atrial fibrillation
- NCT number
- NCT03397602
What you commit to
- Study type: Interventional
- Planned participants: 132
- From 23 Jan 2019 to the primary completion date, 30 Dec 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- unstable angina;
Other
- currently participating in routine exercise training (more than two times per week);
- diagnosed severe mitral or aortic stenosis;
- diagnosed hypertrophic obstructive cardiomyopathy with significant obstruction;
- pregnant, lactating or planning to become pregnant during the study period;
- unable to provide written, informed consent, or
- unwilling or unable to return for follow up at week 12.
Who the study is looking for
- persistent or permanent atrial fibrillation;
- rate controlled with a resting ventricular rate of equal to or less than 100 bpm;
- able to perform a symptom-limited exercise test;
- at least 40 years of age (i.e. participants must be 40 years or older);
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| London Health Sciences Network Coordinator of this site? Confirm its status | London | Canada | Recruiting |
| University of Ottawa Heart Insititue Coordinator of this site? Confirm its status | Ottawa | Canada | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.