NCT03398369Recruiting
Mechanistic Clinical Trial of Advanced Imaging for CRT
Advanced Imaging and Inflammatory Markers to Define Mechanisms of Response to CRT
Source: ClinicalTrials.gov · Last updated 6 Feb 2020 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This is a mechanistic clinical trial with randomization to guidance for the CRT procedure using cardiac magnetic resonance (CMR) and computed tomography angiography (CTA) versus a standard procedure.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 180 (estimated)
- First submitted
- 7 Jan 2018
- Start date
- 5 Jan 2018
- Primary completion date
- 15 Jan 2025
- Lead sponsor
- University of Virginia
- Diseases
- Heart failure
- NCT number
- NCT03398369
What you commit to
- Study type: Interventional
- Planned participants: 180
- From 5 Jan 2018 to the primary completion date, 15 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Presence of metal embedded in the body due to prior accident or injury, as documented by skull films or other imaging
- Cochlear implants
- Other metallic implants known to be contraindications to CMR (does not include pacemakers and ICDs)
- Liver transplant
Other illness
- Gadolinium allergy
Lab values
- Acute renal failure or chronic kidney disease with GFR \< 45 cc/min/1.73m2
Other
- Inability to provide informed consent
- Pregnancy
- Cerebral aneurysm clips
- Severe claustrophobia
- Acute kidney injury
- \>10% premature ventricular contraction (PVC) burden; and 13) estimated \>10% atrial fibrillation (AF) burden based on available clinical data.
Who the study is looking for
- Chronic systolic HF
- LVEF 35% or less
- Guideline-based class I or II indication for CRT
Age in the registry: 20 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Virginia Health System Coordinator of this site? Confirm its status | Charlottesville | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.