NCT03404180CompletedPhase 4
Peripheral Nerve Blocks for Above-the-knee Amputations
Peripheral Nerve Blocks for Upper Leg Amputations
Source: ClinicalTrials.gov · Last updated 8 Jan 2026
Brief summary (registry, in English)
Surgery performed with nerve blocks and sedation may be safer and provide better pain control compared to general anesthesia and opioid therapy in high-risk patient populations such as elderly and troubled with peripheral vascular disease, diabetes, hypertension, coronary artery disease, and chronic obstructive pulmonary disease (COPD).
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 30 (actual)
- First submitted
- 20 Dec 2017
- Start date
- 9 Feb 2018
- Primary completion date
- 18 Dec 2024
- Lead sponsor
- University of Florida
- Diseases
- Coronary artery disease, COPD, High blood pressure
- NCT number
- NCT03404180
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 30
- From 9 Feb 2018 to the primary completion date, 18 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Chronic use of opioid medication
Other illness
- True allergy, not sensitivity, to any of the following substances:
- Severe hepatic impairment
- Evidence of infection at or near the proposed needle insertion site
Other
- Patient refusal or inability to provide informed consent
- \- Local anesthetics
- \- Propofol or other sedative agents
- \- General anesthetic agents
- Pregnancy
- Any sensorimotor deficit, whether acute or chronic, as determined by the PI
- BMI ≥ 35
Who the study is looking for
- Patients undergoing above-the-knee amputation or knee disarticulation
- Ability to understand and provide informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Florida Coordinator of this site? Confirm its status | Gainesville | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.