NCT03418467Active, not recruiting
Risk Factors in Tachycardiomyopathy
Evaluation of Risk Factors for Therapeutic Outcome in Patients with Tachycardiomyopathy
Source: ClinicalTrials.gov · Last updated 28 Mar 2025
Brief summary (registry, in English)
Decision between rate control and rhythm control can be a challenge in clinical practice. While there is some guiding evidence, we still lack a comprehensive insight into different subgroups of patients that will benefit from a rhythm control treatment. EMPATHY is a prospective clinical study in patients presenting with heart failure and a tachyarrhythmic rhythm disturbance. Biomarkers, routinely obtained results from clinical examinations, and results from endomyocardial biopsies shall be evaluated to identify patients which have better outcome from a rhythm control strategy by ablation therapy or, if contraindicated by pharmacological rhythm control. This study is designed to identifying risk factors and subgroups profiting from rhythm restoration and therefore improve current therapeutic approaches and the rate of recurrence-free survival.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 60 (estimated)
- First submitted
- 24 Jan 2018
- Start date
- 11 Oct 2018
- Primary completion date
- 31 Jan 2025
- Lead sponsor
- University Hospital Tuebingen
- Diseases
- Atrial fibrillation
- NCT number
- NCT03418467
What you commit to
- Study type: Observational
- Planned participants: 60
- From 11 Oct 2018 to the primary completion date, 31 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- simultaneous contraindications against amiodarone treatment and pulmonary vein isolation/ablation therapy
- present or suspected alcohol/drug dependency will result in exclusion from the study
Other illness
- relevant valvular disease
Age
- age \<18 years
Other
- patient unable or unwilling to give informed consent
- coronary artery stenosis \>50%
Who the study is looking for
- newly diagnosed left ventricular ejection fraction ≤ 50%
- endomyocardial biopsy available
- tachycardic rhythm disturbance with a rhythm control strategy planned for tachycardic atrial fibrillation or flutter (≥100/min) or more than 10000 ventricular premature beats in 24 hours
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universitätsklinikum Tübingen, Medizinische Klinik III (Kardiologie) Coordinator of this site? Confirm its status | Tübingen | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.