NCT03454828Completed
Mechanisms of Obesity and Its Metabolic Complications in Youth
Source: ClinicalTrials.gov · Last updated 9 Oct 2025
Brief summary (registry, in English)
The overarching goal of this project is to determine whether the effect of gut microbiota on human metabolism might be mediated by short chain fatty acids (SCFA) and whether the SCFA might modulate lipid metabolism.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 38 (actual)
- First submitted
- 19 Feb 2018
- Start date
- 18 Aug 2018
- Primary completion date
- 30 Jun 2024
- Lead sponsor
- Yale University
- Diseases
- Obesity
- NCT number
- NCT03454828
What you commit to
- Study type: Interventional
- Participants enrolled: 38
- From 18 Aug 2018 to the primary completion date, 30 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Food allergies
- Presence of endocrinopathies (e.g. Cushing syndrome)
- Significant chronic illness.
Lab values
- Baseline creatinine \>1.0 mg
Other
- Pregnancy
Who the study is looking for
- Good general health,
- Taking no medication on a chronic basis
- Age 15 to 21 years,
- In puberty (girls and boys: Tanner stage III - V)
- BMI \>25th and \<85th for lean cohort; BMI \>95th for obese cohort
- Girls who begin menstruating must have a negative pregnancy test during the study.
Age in the registry: 15 years to 21 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Research Unit Coordinator of this site? Confirm its status | New Haven | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.