NCT03474575Completed
Early Supported Discharge and Enhanced Homecare After Emergency Department Admission for Acute Exacerbation of COPD
EXADOM: Early Supported Discharge and Enhanced Homecare After Emergency Department Admission for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Source: ClinicalTrials.gov · Last updated 14 May 2024
Brief summary (registry, in English)
The prevalence of chronic obstructive pulmonary disease (COPD) is between 8 and 15% of the adult population in 2010. This prevalence is expected to increase over the coming decades as the population ages and exposure to the risk factors for the disease continues. The evolution of COPD is marked by the occurrence of exacerbations of varying severity responsible for 1% of emergency department admission. Thus,95% of COPD patients admitted to emergency department for exacerbation are hospitalized. Several recent studies seem to show that an early discharge from hospital with home care can reduce the rate of rehospitalisation and mortality of COPD patients. These preliminary data on low numbers need to be confirmed. In addition, it seems necessary to identify the phenotypes of patients who benefit most from these early exits. Exadom project (supported by Rhône-Alpes-Auvergne Regional Health Authorities (ARS), AstraZeneca and Grenoble Alpes University Hospital) aims to establish a safe and effective way of discharging patients by providing enhanced home-based care for AECOPD.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 84 (actual)
- First submitted
- 9 Feb 2018
- Start date
- 19 May 2017
- Primary completion date
- 28 Oct 2023
- Lead sponsor
- University Hospital, Grenoble
- Diseases
- COPD
- NCT number
- NCT03474575
What you commit to
- Study type: Interventional
- Participants enrolled: 84
- From 19 May 2017 to the primary completion date, 28 Oct 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Dementia or non-communicating patient in French language
Other
- Patient unable to call the emergency department at any time in case of sudden worsening
- Pregnancy or breastfeeding woman
- patient under administrative or judicial supervision
- DECAF Score \> 1. Patient's with DECAF score \> 1 are considered at too high risk of mortality to be managed at home (they are usually hospitalized).
Who the study is looking for
- Age ≥ 40 years
- Current or former smoker, with at least 10 pack-years
- previous history of COPD with concordant spirometry results
- Admission to the emergency department for an exacerbation defined as an acute event which is characterized by a degradation of respiratory symptoms greater than the usual daily variations and requiring a change in therapeutic management
- Patient with mild exacerbation characterized by a DECAF score at 0 or 1. (DECAF score: Dyspnea, Eosinopenia, Consolidation on chest x-ray, Acidaemia, and atrial Fibrillation. One point for each criterion. Mortality at one month is less than 3% if the DECAF score is 0 or 1).
- Residence within 30km of Grenoble Alps University Hospital
- Patient legally able to give consent
- Person affiliated to a medical insurance
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Emergency Department of University Hospital Grenoble Coordinator of this site? Confirm its status | Grenoble | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.