NCT03481205Recruiting
Ischemic Conditioning During Air tRansport Save penUmbral Tissue
Source: ClinicalTrials.gov · Last updated 10 Nov 2025
Brief summary (registry, in English)
The purpose of this study is to demonstrate the feasibility of performing remote limb ischemic conditioning (RLIC) using the Doctormate device, a special blood pressure device used to perform RLIC, on patients with acute ischemic stroke due to large vessel occlusion being transported to a thrombectomy capable center by the helicopter.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 10 (estimated)
- First submitted
- 13 Mar 2018
- Start date
- 1 Jun 2020
- Primary completion date
- 1 Dec 2026
- Lead sponsor
- Enrique Leira
- Diseases
- Stroke
- NCT number
- NCT03481205
What you commit to
- Study type: Interventional
- Planned participants: 10
- From 1 Jun 2020 to the primary completion date, 1 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any intracranial hemorrhage (parenchymal, subarachnoid, subdural, epidural) on CT scan at the community hospital
- History of upper or lower extremity ischemia, known subclavian, brachial artery, iliac or femoral artery stenosis, subclavian steal syndrome, any upper or lower extremity soft tissue, orthopedic or vascular injury, or mastectomy or other procedure that may contraindicate taking blood pressure or having a cuff on the arm or leg for the conditioning treatment
- History of diabetes mellitus
- Arteriovenous fistula in upper limb
Age
- Pregnancy. Patients ages 18-55 will need to have a negative urine or blood based pregnancy test.
Other
- Enrollment in another clinical trial
- Patient incarcerated
- Agitation deemed unsafe for ischemic preconditioning testing.
Who the study is looking for
- Age ≥18 and ≤ 80 years
- Suspected acute ischemic stroke with symptoms suggestive of large vessel occlusion (aphasia, agnosia, neglect, visual field cut, and gaze preference).
- Patient screened for rtPA, and rtPA administered if eligible
- Subject or legally authorized representative able to provide consent at the time of the assessment
- NIHSS 6-20
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Iowa Coordinator of this site? Confirm its status | Iowa City | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.