NCT03484702CompletedPhase 2
Trial to Determine the Efficacy and Safety of JCAR017 in Adult Participants With Aggressive B-Cell Non-Hodgkin Lymphoma
A Phase 2, Single-arm, Multi-center Trial to Determine the Efficacy and Safety of JCAR017 in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or With Other Aggressive B-Cell Malignancies
Source: ClinicalTrials.gov · Last updated 27 Dec 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The purpose of this study is to evaluate the efficacy and safety of JCAR017 in participants with aggressive B-cell non-Hodgkin lymphoma (B-NHL)
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 113 (actual)
- First submitted
- 26 Mar 2018
- Start date
- 5 Jun 2018
- Primary completion date
- 15 Dec 2023
- Lead sponsor
- Celgene
- NCT number
- NCT03484702
- EudraCT number
- 2017-000106-38
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 113
- From 5 Jun 2018 to the primary completion date, 15 Dec 2023
- 20 sites in 11 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Received previous CD19-targeted therapy
Other illness
- Progressive vascular tumor invasion, thrombosis, or embolism
- Other protocol-defined inclusion/exclusion criteria apply
Age
- Prior history of malignancies, other than aggressive relapsed/refractory Non-Hodgkin Lymphoma, unless the participant has been in remission for ≥ 2 years with the exception of non-invasive malignancies
Who the study is looking for
- Histological confirmation of diagnosis at last relapse
- Adequate organ function
- Adequate vascular access for leukapheresis procedure
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (20)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Local Institution - 101 Coordinator of this site? Confirm its status | Vienna | Austria | Unknown status |
| Local Institution - 351 Coordinator of this site? Confirm its status | Ghent | Belgium | Unknown status |
| Local Institution - 251 Coordinator of this site? Confirm its status | Bern | Switzerland | Unknown status |
| Local Institution - 151 Coordinator of this site? Confirm its status | Cologne | Germany | Unknown status |
| Local Institution - 152 Coordinator of this site? Confirm its status | Dresden | Germany | Unknown status |
| Local Institution - 155 Coordinator of this site? Confirm its status | Heidelberg | Germany | Unknown status |
| Local Institution - 154 Coordinator of this site? Confirm its status | München | Germany | Unknown status |
| Local Institution - 153 Coordinator of this site? Confirm its status | Ulm | Germany | Unknown status |
| Local Institution - 451 Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Local Institution - 551 Coordinator of this site? Confirm its status | Helsinki | Finland | Unknown status |
| Local Institution - 202 Coordinator of this site? Confirm its status | Lille | France | Unknown status |
| Local Institution - 203 Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Local Institution - 201 Coordinator of this site? Confirm its status | Pierre-Bénite | France | Unknown status |
| Local Institution - 501 Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Local Institution - 502 Coordinator of this site? Confirm its status | Manchester | United Kingdom | Unknown status |
| Local Institution - 402 Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| Local Institution - 401 Coordinator of this site? Confirm its status | Torino | Italy | Unknown status |
| Local Institution - 601 Coordinator of this site? Confirm its status | Chuo-ku | Japan | Unknown status |
| Local Institution - 602 Coordinator of this site? Confirm its status | Minato-ku | Japan | Unknown status |
| Local Institution - 301 Coordinator of this site? Confirm its status | Rotterdam | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.