NCT03486340Completed
Prevention of Chest Pain in Chemo-treated Cancer Patients
Prevention of CArdioToxic-related CHest Pain in Cancer Patients Treated With 5-fluorouracil
Source: ClinicalTrials.gov · Last updated 8 Jul 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This is a prospective, exploratory, randomised clinical trial. Patients with diagnosed cancer that are to be treated with 5-fluorouracil (5-FU) will be randomised into standard oncological treatment or a cardiological assessment prior to the 5-FU treatment. The investigators hypothesize that aggressive management of ischemic risk factors in asymptomatic patients will reduce the number of hospitalisations and investigations for acute coronary syndrome during and after 5-FU treatment and that patients with high coronary artery calcium scores are more likely to experience chest pain during the treatment with 5-FU.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 218 (actual)
- First submitted
- 26 Mar 2018
- Start date
- 11 Apr 2018
- Primary completion date
- 7 Jun 2024
- Lead sponsor
- Vejle Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT03486340
What you commit to
- Study type: Interventional
- Participants enrolled: 218
- From 11 Apr 2018 to the primary completion date, 7 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Ischemia-suspicious symptoms prior to 5-FU treatment
- Ischemia-suspicious ECG-changes prior to 5-FU treatment
Other illness
- Known ischemic heart disease
Who the study is looking for
- Histologically verified cancer
- First-time treatment with 5-FU/Capecitabine
- Expected remaining lifetime \> 6 months
- Informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Departments of Oncology and Medicine, Vejle Hospital Coordinator of this site? Confirm its status | Vejle | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.