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NCT03486340Completed

Prevention of Chest Pain in Chemo-treated Cancer Patients

Prevention of CArdioToxic-related CHest Pain in Cancer Patients Treated With 5-fluorouracil

Source: ClinicalTrials.gov · Last updated 8 Jul 2024 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

This is a prospective, exploratory, randomised clinical trial. Patients with diagnosed cancer that are to be treated with 5-fluorouracil (5-FU) will be randomised into standard oncological treatment or a cardiological assessment prior to the 5-FU treatment. The investigators hypothesize that aggressive management of ischemic risk factors in asymptomatic patients will reduce the number of hospitalisations and investigations for acute coronary syndrome during and after 5-FU treatment and that patients with high coronary artery calcium scores are more likely to experience chest pain during the treatment with 5-FU.

Status (registry)
Completed
Study type
Interventional
Enrollment
218 (actual)
First submitted
26 Mar 2018
Start date
11 Apr 2018
Primary completion date
7 Jun 2024
Lead sponsor
Vejle Hospital
NCT number
NCT03486340

What you commit to

  • Study type: Interventional
  • Participants enrolled: 218
  • From 11 Apr 2018 to the primary completion date, 7 Jun 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Ischemia-suspicious symptoms prior to 5-FU treatment
  • Ischemia-suspicious ECG-changes prior to 5-FU treatment

Other illness

  • Known ischemic heart disease

Who the study is looking for

  • Histologically verified cancer
  • First-time treatment with 5-FU/Capecitabine
  • Expected remaining lifetime \> 6 months
  • Informed consent

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Departments of Oncology and Medicine, Vejle Hospital
Coordinator of this site? Confirm its status
VejleDenmarkUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.