NCT03496792Recruiting
The Venous Distension Reflex and Orthostatic Hypertension
Source: ClinicalTrials.gov · Last updated 9 Jul 2026
Brief summary (registry, in English)
This research is being done to find out whether distension of veins in legs will cause a rise in blood pressure (orthostatic hypertension).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 15 Feb 2018
- Start date
- 10 Mar 2020
- Primary completion date
- 1 Nov 2026
- Lead sponsor
- Milton S. Hershey Medical Center
- Diseases
- High blood pressure
- NCT number
- NCT03496792
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 10 Mar 2020 to the primary completion date, 1 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Have chronic diseases (e.g. heart, lung, neuromuscular disease, or cancer) other than stage I hypertension
- Have orthostatic hypotension or a history of syncope
- History of blood clots
Age
- Age \< 18 years of age
Other
- Are a pregnant or nursing woman
- Are a prisoner or institutionalized individual or unable to consent
- Current smoker
Who the study is looking for
- Are capable of giving informed consent
- Are of any race or ethnicity
- Are fluent in written and spoken English
- Whose history and physical exam did not uncover any exclusion criteria
- Are 18 years of age
- For subjects with elevated standing BP
- Systolic BP (SBP) during standing is at least 10 mmHg \> the supine SBP
- Patients with a diagnosis of stage I hypertension without other chronic diseases may be INCLUDED
- For normal subjects without elevated standing BP
- The change in SBP by standing is within ± 5 mmHg from the supine SBP
- Matched gender, similar age and BMI (within 10%) to participants with elevated standing BP
- Free of acute or chronic medical conditions
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Penn State Milton S. Hershey Medical Center Coordinator of this site? Confirm its status | Hershey | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.