NCT03499509Completed
Obesity Risk in African American Women is Determined by a Diet-by-phenotype Interaction
Source: ClinicalTrials.gov · Last updated 18 May 2025
Brief summary (registry, in English)
The Scientific Premise of this study is that the high level of obesity displayed by African American (AA) women is due to the ability to secrete large amounts of insulin when sugary foods are consumed. When AA women eat a diet rich in starchy or sugary food (a "high-glycemic" diet that stimulates insulin secretion), the food that is eaten is stored as fat rather than being burned as fuel. The investigators previous research has suggested that AA women have an easier time losing weight and keeping it off when eating a low-glycemic diet. The proposed study will be the first randomized clinical trial to test the effect of high and low glycemic diets for weight loss and weight-loss-maintenance in obese AA women.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 67 (actual)
- First submitted
- 4 Apr 2018
- Start date
- 19 Mar 2019
- Primary completion date
- 30 Apr 2024
- Lead sponsor
- University of Alabama at Birmingham
- Diseases
- Obesity
- NCT number
- NCT03499509
What you commit to
- Study type: Interventional
- Participants enrolled: 67
- From 19 Mar 2019 to the primary completion date, 30 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- change in weight greater than 5 pounds in previous 3 months
Other illness
- History of eating disorder
- presence of any condition (e.g. PCOS) or use of any medication (e.g. glucocorticoid) deemed by the project physician to interfere with study outcomes
Lab values
- applicants will be screened with a standard oral glucose tolerance test. If a participant's 2 hour glucose if \>200, they will not be able to enroll in the study.
Other
- daily use of tobacco (\>1 pack/wk)
Who the study is looking for
- BMI 30-45 kg/m2
- Sedentary to moderately active (\<2 hours/wk of moderate, structured, intentional exercise.
- Normal menstrual cycle
Age in the registry: 19 years to 65 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The University of Alabama at Birmingham Coordinator of this site? Confirm its status | Birmingham | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.