NCT03503123Completed
Deventilation Dyspnea in COPD Patients Using NIV
Deventilation Dyspnea in Patients With Chronic Obstructive Pulmonary Disease After Switching Off From Non-invasive Ventilation
Source: ClinicalTrials.gov · Last updated 10 May 2024
Brief summary (registry, in English)
Non-invasive ventilation (NIV) has shown to be an effective therapy for patients with Chronic Obstructive Pulmonary Disease (COPD) with Chronic Hypercapnic Respiratory Failure (CHRF). However, these COPD patients often report severe dyspnoea after switching off from NIV therapy, which leads to discomfort and distress. Currently, it is not known what causes this deventilation dyspnoea and therefore a possible treatment to prevent deventilation dyspnoea is not available. This study investigates possible mechanisms underlying the phenomenon of deventilation dyspnoea in COPD patients by monitoring the effects of NIV on the patient during an afternoon sleep.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 10 (actual)
- First submitted
- 9 Apr 2018
- Start date
- 15 Aug 2019
- Primary completion date
- 15 Dec 2023
- Lead sponsor
- University Medical Center Groningen
- Diseases
- COPD
- NCT number
- NCT03503123
What you commit to
- Study type: Observational
- Participants enrolled: 10
- From 15 Aug 2019 to the primary completion date, 15 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Having other disorders leading to respiratory failure (such as morbid obesity, kyphoscoliosis, neuromuscular diseases, tuberculosis)
- Having spinal injury, BMI\>50, damaged or inflamed skin around the thorax or a cardiac pacemaker or other implanted devices
Other
- COPD exacerbation within 2 weeks preceding the study
- Modification of ventilation within 2 weeks preceding the study
- Having a poor compliance with NIV (usage of \<4 h/day)
- Not being able to sleep 1.5 hour in the afternoon
Who the study is looking for
- COPD with a NIV indication using chronic NIV
- Age \> 18 years
- With or without deventilation dyspnea when switching off from NIV (depending on group/cohort)
- Written informed consent is obtained
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Pulmonary diseases Coordinator of this site? Confirm its status | Groningen | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.