NCT03503331RecruitingPhase 2
UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy
Source: ClinicalTrials.gov · Last updated 12 Aug 2026
Brief summary (registry, in English)
The primary objective of this study is to measure the concentration and the regional brain distribution of pathologic amyloid deposition using the PET tracer \[C-11\]PiB in participants in the UAB Alzheimer's Disease Center cohort. Assessment of interactions between race and vascular risk factors, brain amyloid levels measured with \[C-11\]PiB-PET, and cognitive status will be the primary outcome of this imaging study.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 160 (estimated)
- First submitted
- 26 Feb 2018
- Start date
- 20 Apr 2018
- Primary completion date
- 31 Oct 2028
- Lead sponsor
- University of Alabama at Birmingham
- Diseases
- Alzheimer disease
- NCT number
- NCT03503331
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 160
- From 20 Apr 2018 to the primary completion date, 31 Oct 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Inability to participate in the imaging studies due to severity of dementia
Other
- Meets any exclusion criteria for the UAB-ADC study (IRB-300000169).
- Inability or contraindication for undergoing MRI and/or PET imaging
Who the study is looking for
- \- 1. Enrollment in the UAB-ADC study under a separate IRB-approved research protocol (IRB-300000169).
- 2\. Negative urine or serum B-hCG test within 2 days of \[C-11\]PiB administration in women of child bearing potential. Women who are post-menopausal with at least 1 year since last menses or documented surgical sterilization will not require pregnancy testing.
Age in the registry: 50 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Alabama at Birmingham Medical Center Coordinator of this site? Confirm its status | Birmingham | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.