NCT03505216Recruiting
Swiss Paediatric Airway Cohort
Source: ClinicalTrials.gov · Last updated 21 Apr 2026
Brief summary (registry, in English)
The Swiss Paediatric Airway Cohort (SPAC) is a national, prospective clinical cohort of children and adolescents who visit physicians in Switzerland for recurrent wheeze, cough, and exercise- or sleep-related respiratory problems. SPAC aims to answer important questions on clinical phenotypes, prognosis, diagnosis and treatment. SPAC is part of routine care, and only clinically indicated investigations are done. The comprehensive baseline assessment includes a detailed questionnaire to families, plus test results, diagnoses and treatments from hospital records. Follow-up is via monthly questionnaires the first 12 months and thereafter annual questionnaires to families, and data from follow-up visits. Currently, 4344 patients from 10 clinics and hospitals in Switzerland (Aarau, Basel, Bern, Chur, Horgen, Lausanne, Luzern, St. Gallen, Worb, Zurich) have been enrolled. SPAC provides real-life data on children visiting the Swiss health care system for common respiratory problems. It will provide a research platform for health services research, and for nested clinical and transitional studies. Publications and plain language summaries are listed on the study website: https://www.spac-study.ch/publikationen/
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 6000 (estimated)
- First submitted
- 2 Apr 2018
- Start date
- 6 Jun 2017
- Primary completion date
- 1 Sept 2026
- Lead sponsor
- University of Bern
- Diseases
- Asthma
- NCT number
- NCT03505216
What you commit to
- Study type: Observational
- Planned participants: 6000
- From 6 Jun 2017 to the primary completion date, 1 Sept 2026
- 12 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior diagnosis of cystic fibrosis, primary ciliary dyskinesia, severe heart disease, oncological disease, neuromuscular disease or severe disability
Who the study is looking for
- Children and adolescents aged 0-16 years
- Resident in Switzerland
- Seen in a paediatric pulmonary outpatient clinic due to respiratory problems
- Parents and patients above age 14 must be able to sign an informed consent form
Age in the registry: 0 years to 16 years · Sex: All · Does not accept healthy volunteers
Sites (12)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Vienna Open Medical Institute Coordinator of this site? Confirm its status | Vienna | Austria | Completed |
| Children's hospital Aarau Coordinator of this site? Confirm its status | Aarau | Switzerland | Active, not recruiting |
| University Children's Hospital Basel (UKBB) Coordinator of this site? Confirm its status | Basel | Switzerland | Recruiting |
| Institute of Social and Preventive Medicine Coordinator of this site? Confirm its status | Bern | Switzerland | Recruiting |
| University Children's Hospital Bern, Inselspital Coordinator of this site? Confirm its status | Bern | Switzerland | Recruiting |
| Children's Hospital Chur Coordinator of this site? Confirm its status | Chur | Switzerland | Recruiting |
| Pulmonology clinic, Horgen Coordinator of this site? Confirm its status | Horgen | Switzerland | Recruiting |
| University Children's hospital Lausane, CHUV Coordinator of this site? Confirm its status | Lausanne | Switzerland | Recruiting |
| Children's hospital Lucerne Coordinator of this site? Confirm its status | Lucerne | Switzerland | Recruiting |
| Children's hospital St. Gallen Coordinator of this site? Confirm its status | Sankt Gallen | Switzerland | Active, not recruiting |
| Pulmonology clinic, Worb Coordinator of this site? Confirm its status | Worb | Switzerland | Recruiting |
| University Children's Hospital Zurich Coordinator of this site? Confirm its status | Zurich | Switzerland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.