NCT03528226Recruiting
Exercise Training and Endothelial Function in Type 1 Diabetes
Impact of Exercise Training on Endothelial Function in Adults With Type 1 Diabetes
Source: ClinicalTrials.gov · Last updated 14 May 2026
Brief summary (registry, in English)
Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T1D). In a preventive setting, in T1D patients still free of complications, the research of non-pharmacological interventions to improve endothelial function appears fundamental. In this randomized controlled trial, the effects of exercise training on endothelial function will be evaluated in T1D adults. Secondary objectives are to evaluate the exercise training effects on the micro and macrovascular function and exercise-induced tissue vasoreactivity and their possible neurometabolic consequences. An improvement in vascular function, particularly endothelium-dependent, as well as in neurometabolic profile, through this non-pharmacological strategy is expected
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 34 (estimated)
- First submitted
- 3 May 2018
- Start date
- 12 Nov 2019
- Primary completion date
- Nov 2028
- Lead sponsor
- University Hospital, Lille
- Diseases
- Type 1 diabetes
- NCT number
- NCT03528226
What you commit to
- Study type: Interventional
- Planned participants: 34
- From 12 Nov 2019 to the primary completion date, Nov 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- type 1 diabetes diagnoses for less than 1 year
- MODY diabetes, mitochondrial diabetes or type 2 diabetes
- Hypertension
- Active chronic disease or in remission (excluding type 1 diabetes)
Other
- presence of macrovascular and/or microvascular diabetic complications (retinopathy, nephropathy, neuropathy ,…)
- Obesity (Body Mass Index \> 30 kg/m²
- Smokers
- Disabling painful discomfort for trunk, upper or lower limb movements
- Head trauma in the past
Who the study is looking for
- Covered by social security
- With a T1Diabete, diagnosed for at least 1 year, and free from macrovascular and microvascular diabetic complications.
Age in the registry: 18 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hop Claude Huriez Chu Lille Coordinator of this site? Confirm its status | Lille | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.