NCT03535623Completed
RIPC During Free Flap With Preoperative Radiotherapy
Effects of Remote Ischemic Preconditioning During Free Flap Reconstruction in Head and Neck Cancer Patients With Preoperative Radiotherapy
Source: ClinicalTrials.gov · Last updated 11 Jun 2026
Brief summary (registry, in English)
Remote ischemic preconditioning (RIPC) has shown organ-protective effects in many clinical settings including patients with ischemic heart disease. However its protective role in head and neck cancer patients with preoperative radiotherapy undergoing free flap reconstructive surgery has not yet been evaluated. The purpose of the current study is to evaluate the effect of RIPC on tissue oxygen saturation and skin temperature of the flap.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 44 (actual)
- First submitted
- 14 May 2018
- Start date
- 29 May 2018
- Primary completion date
- 20 Mar 2024
- Lead sponsor
- Seoul National University Hospital
- Diseases
- Head and neck cancer
- NCT number
- NCT03535623
What you commit to
- Study type: Interventional
- Participants enrolled: 44
- From 29 May 2018 to the primary completion date, 20 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Radiotherapy within 4 weeks
Other illness
- Presence of AV fistula at the arm, any reason to protect arms
- Peripheral vascular disease, peripheral neuropathy, or coagulopathy
- Uncontrolled diabetes mellitus
Other
- Body mass index \< 18 kg/m\^2 or \> 35 kg/m\^2
- Presence of vascular abnormality or discomfort at arms
- Preoperative use of beta-blockers
- Refuse to enrol
Who the study is looking for
- Adult head and neck cancer patients undergoing free flap reconstructive surgery with preoperative radiotherapy
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Seoul National University Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.