NCT03541096Active, not recruiting
Winter-Swimming and Brown Adipose Tissue Activity in Middel-aged Obese Subjects (WinterBAT).
The Impact of Winter Swimming on Brown Adipose Tissue Recruitment and Metabolic Health in Middel-aged Obese Pre-diabetic Subjects.
Source: ClinicalTrials.gov · Last updated 17 Aug 2025
Brief summary (registry, in English)
This study investigates repetitive cold-water exposure on brown fat activity assessed by PET/CT scanning. Furthermore we will assess glucose control upon winter-swimming. Obese prediabetic men and women will be randomized to winter-swimming or control conditions for 4 months.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 30 (actual)
- First submitted
- 17 May 2018
- Start date
- 7 Nov 2018
- Primary completion date
- 1 Jun 2021
- Lead sponsor
- Kristian Karstoft
- Diseases
- Obesity, Type 1 diabetes, Type 2 diabetes
- NCT number
- NCT03541096
What you commit to
- Study type: Interventional
- Participants enrolled: 30
- From 7 Nov 2018 to the primary completion date, 1 Jun 2021
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any history of Cancer,
- Clinically significant liver, kidney, heart, inflammatory or lung-disease.
- Abnormal ultrasound echocardiography of the heart found at the health-examination day.
- Contraindications to cold exposure including severe Raynauds disease.
- History of alcohol abuse or use of more than 14 units pr. Week.
- History of drug abuse, including marihuana.
- History of contrast allergy.
Lab values
- Taking medication (not for hay fever), including glucose-lowering treatment.
- HbA1c \>55 mmol/mol and/or 2-h plasma glucose in the 75-g OGTT \> 15 mmol/L, fasting plasma glucose above 6.9.
- Increased International Normalised Ratio for coagulation (INR).
Other
- Winter swimmer
- Pregnancy
- Iron deficiency
- Femoral hernia, vene prostheses (pants prosthesis), thrombs in v. Femoralis.
- Smoking including occasional smoking.
- Pacemaker or other electronics implanted in the body.
- Claustrophobia, communication problems, including understanding the experimental protocol.
Who the study is looking for
- Waist circumference above 80 cm for women and 94 cm for men.
- BMI \> 25 but \<40 kg/m2
- Age \> 40 years.
- Low to moderate physical activity level (no physical activity or on average 30 minutes of moderate physical activity per day and not more than 3 hours of training pr. Week)
- Subjects will be included in either one of these cases after the screening:
- Fasting plasma glucose above 5.6 millimol per liter (mmoL/L).
- HbA1C \>39 millimol per mol (mmol/mol).
- 2 hour plasma glucose after a 75 g. oral glucose tolerance test (OGTT) above 7.8 mmol/L.
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Center for Inflammation and Metabolism/ Center for Physical Activity Research Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.