NCT03548506Completed
Subthalamic Steering for Therapy Optimization in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 3 Jun 2026
Brief summary (registry, in English)
Twenty patients with idiopathic Parkinson's disease (PD) will be included into this single center randomized controlled double-blind clinical trial (RCT) in a cross-over design. The treatment consists of two different stimulation settings using (i) conventional omnidirectional stimulation of the subthalamic nucleus \[STN\_O\] as active comparator and (ii) directional steering of STN stimulation via a segmented electrode contact \[STN\_D\].
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 18 Apr 2018
- Start date
- 19 Apr 2018
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- University Hospital Tuebingen
- Diseases
- Parkinson disease
- NCT number
- NCT03548506
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 19 Apr 2018 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cognitive impairment (Mini Mental State Exam \< 20)
- Other severe pathological chronic condition that might confound treatment effects or interpretation of the data
Other
- Suicidality, Psychosis
- Pregnancy
Who the study is looking for
- Written informed consent
- Idiopathic Parkinson's disease (according to the "British Brain Bank criteria" (Hughes, 1992) including genetic forms
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Tuebingen, Dep. of Neurosurgery (Functional Neurosurgery) and Neurology (Neurodegenerative Diseases) Coordinator of this site? Confirm its status | Tübingen | Germany | Unknown status |
Related publications
- Subthalamic stimulation modulates working memory-related cortical dynamics in Parkinson's disease.Brain Commun · 2026 · PMID 42712895
This page is information, not medical advice. Discuss any trial with your doctor.