NCT03552965Completed
Margin-Based Vs. Robust Photon Radiotherapy Planning in IMRT of HN-SQCC
Prospective Randomized Pilot Clinical Trial of Margin-Based Vs. Robust Photon Radiotherapy Planning in Intensity-Modulated Radiation Therapy of Squamous-Cell Carcinoma of the Head and Neck
Source: ClinicalTrials.gov · Last updated 2 Sept 2025
Brief summary (registry, in English)
This is a research study to evaluate the quality of life and amount of dry mouth experienced as a result of radiotherapy in subjects who have squamous cell carcinoma of the head and neck (HN-SQCC). This study will compare the side effects experienced based on the method to plan radiotherapy, Margin Based or Robust.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 23 (actual)
- First submitted
- 7 May 2018
- Start date
- 19 Jun 2018
- Primary completion date
- 9 Mar 2024
- Lead sponsor
- University of Arkansas
- Diseases
- Head and neck cancer
- NCT number
- NCT03552965
What you commit to
- Study type: Interventional
- Participants enrolled: 23
- From 19 Jun 2018 to the primary completion date, 9 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of saliva stimulating prescription drugs such as Evoxac or Salagen
- Unable to receive standard chemotherapy
Other
- Women with a positive urine pregnancy test are excluded from this study; women of childbearing potential must agree to refrain from breast feeding and practice adequate contraception
- Unable to comply with study procedures
Who the study is looking for
- Histological documentation of Squamous-Cell Carcinoma of the Head and Neck (HN-SQCC)
- Older than 21 years of age
- Subject is eligible for routine chemo-radiotherapy for treatment of HN-SQCC
- Informed consent is obtained
- Karnofsky performance of at least 70 points
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Arkansas for Medical Sciences Coordinator of this site? Confirm its status | Little Rock | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.